{"id":"W2144897051","doi":"10.1002/arch.10124","title":"Morphological and molecular effects of 20‐hydroxyecdysone and its agonist tebufenozide on CF‐203, a midgut‐derived cell line from the spruce budworm, <i>Choristoneura fumiferana</i>","year":2004,"lang":"en","type":"article","venue":"Archives of Insect Biochemistry and Physiology","topic":"Insect and Arachnid Ecology and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Natural Resources Canada; Canadian Forest Service","funders":"Krell Institute; Genome Canada","keywords":"Ecdysone; 20-Hydroxyecdysone; Ecdysteroid; Spruce budworm; Biology; Choristoneura fumiferana; Agonist; Ecdysterone; Cell culture; Midgut; Ecdysone receptor; Internal medicine; Endocrinology; Transcription factor; Cell biology; Receptor; Biochemistry; Botany; Lepidoptera genitalia; Hormone; Tortricidae; Nuclear receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008765993,0.000251787,0.000210396,0.0001136146,0.0001360917,0.0001902306,0.0001410569,0.0003033844,0.0009661948],"category_scores_gemma":[0.0000650904,0.0001342877,0.0002302181,0.0001299639,0.0001745462,0.0001542561,0.0001001079,0.0004270506,0.0003791176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003255202,"about_ca_system_score_gemma":0.0001795068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002410159,"about_ca_topic_score_gemma":0.004536276,"domain_scores_codex":[0.9999104,0.00001818608,0.000008578731,0.00001601674,0.00002300572,0.00002384468],"domain_scores_gemma":[0.9999057,0.00003155104,0.00001499164,0.00001177143,0.00001058903,0.00002530762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001071559,0.000009907235,0.0001020251,0.00001786131,0.000002096005,0.00005194531,0.00001014512,0.00001704541,0.9993062,0.00001527437,0.00001859035,0.0003416409],"study_design_scores_gemma":[0.00001664682,0.0004509739,0.01710247,0.000004565825,0.0000123487,0.0002502947,0.00007544243,0.0002558894,0.9802525,0.0000156221,0.001557493,0.000005701097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931691,0.00232553,0.0005828642,0.0001077435,0.00003035761,0.00002041193,0.001024941,0.00002983829,0.002709205],"genre_scores_gemma":[0.9914471,0.001290865,0.001215692,0.0000977724,0.000008863593,0.00003365366,0.001456881,0.000009352335,0.004439763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002410159,"threshold_uncertainty_score":0.004792273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00572948141391677,"score_gpt":0.2104606204072933,"score_spread":0.2047311389933765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}