{"id":"W2144897051","doi":"10.1002/arch.10124","title":"Morphological and molecular effects of 20‐hydroxyecdysone and its agonist tebufenozide on CF‐203, a midgut‐derived cell line from the spruce budworm, <i>Choristoneura fumiferana</i>","year":2004,"lang":"en","type":"article","venue":"Archives of Insect Biochemistry and Physiology","topic":"Insect and Arachnid Ecology and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Natural Resources Canada; Canadian Forest Service","funders":"Krell Institute; Genome Canada","keywords":"Ecdysone; 20-Hydroxyecdysone; Ecdysteroid; Spruce budworm; Biology; Choristoneura fumiferana; Agonist; Ecdysterone; Cell culture; Midgut; Ecdysone receptor; Internal medicine; Endocrinology; Transcription factor; Cell biology; Receptor; Biochemistry; Botany; Lepidoptera genitalia; Hormone; Tortricidae; Nuclear receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006099859,0.0002724418,0.0003629683,0.00002362734,0.0001537619,0.000007288876,0.0001885881,0.0002568125,0.000006186181],"category_scores_gemma":[0.00006729139,0.0002034781,0.00009818133,0.000049073,0.0007791548,0.000004536396,0.000195242,0.0002437139,7.23518e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003048051,"about_ca_system_score_gemma":0.00003604253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006778224,"about_ca_topic_score_gemma":0.000009000863,"domain_scores_codex":[0.9988238,0.0001025627,0.0002611511,0.0004958329,0.00006264226,0.0002539816],"domain_scores_gemma":[0.9992404,0.0001962764,0.0001620316,0.00028455,0.00002504571,0.00009171577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006958009,0.0002676967,0.000495926,0.0001664506,0.00006535686,0.00002580113,0.0001409401,0.00001777373,0.9976658,0.0000545637,0.0000176851,0.0003861578],"study_design_scores_gemma":[0.001467962,0.00121871,0.01524862,0.00004981898,0.00007104753,0.00003944368,0.00003331461,0.00001344162,0.9806954,0.0009176556,0.00003175451,0.000212876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952358,0.003994817,0.00003938913,0.0002162613,0.00005704137,0.0002056617,0.0001022935,0.000008089868,0.0001406268],"genre_scores_gemma":[0.9975853,0.001307267,0.0002243339,0.0005158922,0.0001080402,0.00002168251,0.0001827763,0.00001502481,0.00003966075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01697049,"threshold_uncertainty_score":0.8297595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00572948141391677,"score_gpt":0.2104606204072933,"score_spread":0.2047311389933765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}