{"id":"W2144980404","doi":"10.1002/glia.20335","title":"Hypoxia-activated microglial mediators of neuronal survival are differentially regulated by tetracyclines","year":2006,"lang":"en","type":"article","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Neuroprotection; Microglia; Minocycline; Glial cell line-derived neurotrophic factor; Neurotrophic factors; Biology; Hypoxia (environmental); Neurotrophin; Pharmacology; Neuroglia; Tumor necrosis factor alpha; Neuroscience; Inflammation; Immunology; Central nervous system; Biochemistry; Chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111542,0.0002106216,0.0002780771,0.0001473969,0.0001168403,0.0002447403,0.00007944457,0.0001707956,0.0007539328],"category_scores_gemma":[0.0001349585,0.0001009348,0.0001991974,0.0001029819,0.0001938071,0.0001535299,0.0001427491,0.0002201846,0.0001148562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002557439,"about_ca_system_score_gemma":0.0001225131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004790257,"about_ca_topic_score_gemma":0.0008639115,"domain_scores_codex":[0.9998752,0.00002397966,0.00001050416,0.00001818178,0.00002690183,0.00004522806],"domain_scores_gemma":[0.9998685,0.00002089659,0.00005618121,0.000009023065,0.00002114366,0.00002433154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002692223,0.00001347251,0.0001535577,0.00004260577,0.000003547812,0.00004510137,0.00002571421,0.0000159058,0.9985226,0.00004155099,0.00002159613,0.0008451416],"study_design_scores_gemma":[0.00004553794,0.0006522521,0.03309074,0.0000274982,0.00004066061,0.0003100149,0.000150977,0.0006156455,0.9614584,0.0001006734,0.003497634,0.00001008116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909507,0.006084546,0.00112571,0.0001238498,0.00002990852,0.00001856914,0.0001765237,0.00002799372,0.001462099],"genre_scores_gemma":[0.9956196,0.002022575,0.0006717896,0.00005241524,0.00001941883,0.00005054666,0.0001858744,0.000008700737,0.001369068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007539328,"threshold_uncertainty_score":0.002522171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541389907354692,"score_gpt":0.2285228386769896,"score_spread":0.2131089396034427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}