{"id":"W2144992128","doi":"10.1086/520592","title":"Blockage of Filoviral Glycoprotein Processing by Use of a Protein‐Based Inhibitor","year":2007,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Manitoba; Public Health Agency of Canada","funders":"U.S. Army Medical Research Institute of Infectious Diseases; Canadian Institutes of Health Research; Centers for Disease Control and Prevention; Yale University; Public Health Agency of Canada; National Institutes of Health; University of Tokyo; Public Health Agency","keywords":"Furin; Glycoprotein; Virology; Infectivity; Proteases; Virus; Ebola virus; Biology; Viral replication; NS2-3 protease; Cleavage (geology); Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000661488,0.0001365096,0.0003734803,0.0003088575,0.000106199,0.00002151538,0.00009353524,0.00006521523,0.0001167563],"category_scores_gemma":[0.0005559293,0.00008260053,0.0002299778,0.0005002562,0.0002564165,0.0002073096,0.000031346,0.0003133345,0.00000216489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008340814,"about_ca_system_score_gemma":0.0003670437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002384066,"about_ca_topic_score_gemma":0.00001746674,"domain_scores_codex":[0.9983486,0.0001142046,0.000659338,0.00008114275,0.0005629854,0.0002337429],"domain_scores_gemma":[0.9981208,0.0001689327,0.0006024106,0.0001825737,0.0007372256,0.000188094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00488055,0.002832356,0.07688247,0.0009186911,0.0002374483,0.00007568404,0.0002071832,0.0001986139,0.884352,0.0000170049,0.002139722,0.02725834],"study_design_scores_gemma":[0.005301169,0.006481172,0.03906295,0.001734069,0.0006067313,0.0003775777,0.0002510146,0.0004173171,0.9438899,0.0001252362,0.001541874,0.0002110403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947994,0.001054516,0.003217994,0.0001514053,0.00004613718,0.0004826839,0.00002896677,0.00001812808,0.0002007279],"genre_scores_gemma":[0.999363,0.00002723246,0.0001491124,0.00007497386,0.0001727527,0.000004541745,0.000002841902,0.0000209047,0.0001846517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05953791,"threshold_uncertainty_score":0.3368352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01784739793543189,"score_gpt":0.2976234125828564,"score_spread":0.2797760146474245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}