{"id":"W2145010689","doi":"10.1038/emboj.2010.106","title":"Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo","year":2010,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":587,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; National Institutes of Health; Academy of Finland","keywords":"Biology; Chromatin immunoprecipitation; Genetics; Transcription factor; ChIP-sequencing; DNA; DNA-binding protein; DNA binding site; Computational biology; ChIP-on-chip; Binding site; Chromatin; DNA microarray; Plasma protein binding; Immunoprecipitation; Gene; Promoter; Cell biology; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008492409,0.00006205396,0.0001442042,0.0002181082,0.00005299269,0.00002641093,0.0001773273,0.00005031979,0.00002288231],"category_scores_gemma":[0.0001139678,0.00004346477,0.00006546031,0.0002501931,0.00005805427,0.00000383968,0.00006876952,0.0003098841,5.57391e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008757617,"about_ca_system_score_gemma":0.00004433141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003592364,"about_ca_topic_score_gemma":0.0003400835,"domain_scores_codex":[0.9993222,0.00006959336,0.0001916697,0.0001001211,0.0001152942,0.0002011464],"domain_scores_gemma":[0.9996602,0.00002996192,0.00006733363,0.0001471918,0.00003030346,0.00006503831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009851279,0.00001498687,0.02536422,0.00000223435,0.00008326322,0.00001093148,0.00007682717,0.00008308236,0.9738122,0.000002609377,0.0000217924,0.0004293068],"study_design_scores_gemma":[0.0007034824,0.00007270629,0.3032793,0.00001005979,0.00005959538,0.00005502536,0.0004852659,0.001270273,0.6930559,0.00007376047,0.0008153133,0.0001193869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990566,0.0002447573,0.0000467981,0.0001848964,0.00003166749,0.00004130593,0.000004321498,7.014242e-7,0.0003889946],"genre_scores_gemma":[0.9992529,0.0002694702,0.0001261419,0.00007726377,0.00005987985,0.000001390942,0.000003082404,0.000005630056,0.0002042617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2807564,"threshold_uncertainty_score":0.1772442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009994212396713472,"score_gpt":0.2701100025882322,"score_spread":0.2601157901915187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}