{"id":"W2145010689","doi":"10.1038/emboj.2010.106","title":"Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo","year":2010,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":587,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; National Institutes of Health; Academy of Finland","keywords":"Biology; Chromatin immunoprecipitation; Genetics; Transcription factor; ChIP-sequencing; DNA; DNA-binding protein; DNA binding site; Computational biology; ChIP-on-chip; Binding site; Chromatin; DNA microarray; Plasma protein binding; Immunoprecipitation; Gene; Promoter; Cell biology; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003652108,0.0002889737,0.0003525804,0.000433653,0.0001964483,0.0003551219,0.0002027088,0.0002937173,0.001044265],"category_scores_gemma":[0.0003230032,0.000220932,0.0003768972,0.0004622346,0.0001808007,0.00009930687,0.0002053867,0.0005360554,0.0004823081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002576728,"about_ca_system_score_gemma":0.000152335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001575648,"about_ca_topic_score_gemma":0.005259492,"domain_scores_codex":[0.9997569,0.00003065036,0.0000116072,0.0001086595,0.00006224252,0.00003003598],"domain_scores_gemma":[0.9997275,0.00009887061,0.00006243177,0.00002837649,0.0000445609,0.00003817491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001037233,0.0000146806,0.004487492,0.0000500071,0.00006989721,0.00002676192,0.00002833175,0.0001816284,0.9929777,0.00005737647,0.0001023394,0.001900195],"study_design_scores_gemma":[0.00002223163,0.0001505221,0.5071044,0.0000100362,0.0002224711,0.0006748384,0.00008018281,0.00406536,0.4803084,0.000191622,0.007141588,0.00002840038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886143,0.001484834,0.004106218,0.00005744974,0.00001092754,0.000008992411,0.004893213,0.00006221533,0.0007617974],"genre_scores_gemma":[0.9739631,0.001014737,0.006114845,0.0001303844,0.000009869847,0.00003467315,0.01645875,0.00006857346,0.002205017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001575648,"threshold_uncertainty_score":0.003493428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009994212396713472,"score_gpt":0.2701100025882322,"score_spread":0.2601157901915187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}