{"id":"W2145014826","doi":"10.1128/aem.01138-14","title":"Analysis of Strains Lacking Known Osmolyte Accumulation Mechanisms Reveals Contributions of Osmolytes and Transporters to Protection against Abiotic Stress","year":2014,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Osmolyte; Osmoprotectant; Betaine; Dimethylsulfoniopropionate; Chemistry; Biochemistry; Trehalose; Osmotic shock; Glycine; Abiotic stress; Ectoine; Proline; Amino acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001094555,0.0001114587,0.0002195202,0.00009110897,0.00004974691,0.000002946971,0.00004077205,0.0001405968,0.000007914303],"category_scores_gemma":[0.000002627148,0.0001094129,0.00005539369,0.0000764771,0.0001117889,0.000003238769,0.00001741832,0.00003506415,3.185458e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008819916,"about_ca_system_score_gemma":0.000003438096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001029524,"about_ca_topic_score_gemma":0.00002373396,"domain_scores_codex":[0.9993489,0.00002383303,0.0002330819,0.0002419404,0.00003041672,0.0001217928],"domain_scores_gemma":[0.9997292,0.000006593327,0.0001071261,0.0001077156,0.000007891774,0.00004150227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004546134,0.00004066704,0.003543705,0.00002090241,0.000157288,7.196843e-8,0.0001306268,0.001158296,0.9918107,0.0002194307,9.598619e-7,0.002871858],"study_design_scores_gemma":[0.0004943378,0.0001929307,0.1289936,0.00001165648,0.000231984,0.000001543684,0.0001750345,0.0003208588,0.8692267,0.000130048,0.00008626855,0.0001351075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9684688,0.00004638822,0.03084042,0.00002991718,0.00001978473,0.0002476597,0.0003223779,0.000003919154,0.00002068818],"genre_scores_gemma":[0.9977357,0.00005262219,0.0002004457,0.0000521825,0.00001688762,0.00001177135,0.001911216,0.000007668087,0.00001144639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1254499,"threshold_uncertainty_score":0.4461729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006057784749023125,"score_gpt":0.2045068667463063,"score_spread":0.1984490819972832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}