{"id":"W2145016172","doi":"10.1038/nn.2702","title":"Retinoid X receptor gamma signaling accelerates CNS remyelination","year":2010,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":549,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Nautical Research Society","funders":"Parkinson's UK; Wellcome Trust","keywords":"Remyelination; Oligodendrocyte; Biology; Retinoid X receptor; Retinoic acid; Multiple sclerosis; Myelin; Neuroscience; Cell biology; Central nervous system; Nuclear receptor; Immunology; Transcription factor; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004079745,0.0003370836,0.0002297996,0.0002432219,0.000704922,0.0003657799,0.001122772,0.0003256913,0.0001496199],"category_scores_gemma":[0.006336794,0.0003026798,0.0001135943,0.001284426,0.0002996162,0.0006061466,0.0002232586,0.001962185,0.000158897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001748505,"about_ca_system_score_gemma":0.00009457261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001307748,"about_ca_topic_score_gemma":0.000003414431,"domain_scores_codex":[0.9963314,0.000207884,0.0003701341,0.00138969,0.001026646,0.0006742385],"domain_scores_gemma":[0.9982234,0.0005685558,0.0002286145,0.0005711903,0.0001349375,0.000273335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002544668,0.00007498337,0.00008154441,0.000007699031,1.908114e-7,0.00004506556,0.00002683992,0.00002939715,0.9902835,0.008176644,0.0003552031,0.0008934687],"study_design_scores_gemma":[0.0002026844,0.0001496714,0.0008813577,0.00001002452,0.000005584727,0.0001293898,0.000004640439,0.001390031,0.9793451,0.0002394908,0.01734355,0.0002985218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897228,0.00001094839,0.0003244621,0.001076792,0.00706106,0.0003318304,0.00002607588,0.0003613855,0.001084636],"genre_scores_gemma":[0.9910774,0.00004414748,0.0005368073,0.007404319,0.0004160636,0.0000203133,0.000001681824,0.00005363013,0.0004456108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01698834,"threshold_uncertainty_score":0.9999425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02359907516546985,"score_gpt":0.2779733058154161,"score_spread":0.2543742306499463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}