{"id":"W2145035318","doi":"10.2967/jnumed.111.095653","title":"Quantitative Preclinical Imaging of TSPO Expression in Glioma Using <i>N,N</i>-Diethyl-2-(2-(4-(2-<sup>18</sup>F-Fluoroethoxy)Phenyl)-5,7-Dimethylpyrazolo[1,5-<i>a</i>]Pyrimidin-3-yl)Acetamide","year":2012,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Cancer Institute; McGill University","keywords":"Translocator protein; Radioligand; In vivo; Chemistry; Molecular imaging; Glioma; Nuclear medicine; In vitro; Pathology; Cancer research; Medicine; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003203322,0.000545902,0.0002093884,0.0002095971,0.0001131065,0.0002648558,0.0004164971,0.0003475257,0.0007743528],"category_scores_gemma":[0.0002461509,0.000183942,0.0001405022,0.0001520024,0.0003314258,0.0003014518,0.0001264577,0.0003790052,0.0002232558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005609753,"about_ca_system_score_gemma":0.0004126626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003180527,"about_ca_topic_score_gemma":0.003055349,"domain_scores_codex":[0.9998873,0.0000282552,0.000004374969,0.00002119008,0.00002856039,0.00003014528],"domain_scores_gemma":[0.9998819,0.00003159575,0.00004040072,0.000006895933,0.00002016153,0.00001912726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002671853,0.00004667085,0.0001447049,0.00005299921,0.000005817752,0.00001904946,0.00001075057,0.0003834646,0.997309,0.00005768249,0.00004906911,0.001653766],"study_design_scores_gemma":[0.00003154688,0.001220669,0.00134087,0.000004206619,0.00002916838,0.0001401687,0.0000187564,0.003591316,0.9928537,0.00001608785,0.0007462305,0.000007360448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740897,0.002070933,0.02086996,0.0001288413,0.0000200299,0.0001228596,0.0003438878,0.0003195226,0.002034341],"genre_scores_gemma":[0.9689947,0.001804265,0.02627596,0.00005347648,0.00001186338,0.0001728507,0.000497559,0.00005883569,0.002130408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003180527,"threshold_uncertainty_score":0.006324053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07201743405432284,"score_gpt":0.3676449060000661,"score_spread":0.2956274719457432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}