{"id":"W2145044998","doi":"10.1081/lpr-120004793","title":"AVOIDING UNTOWARD IMMUNE RESPONSES TO NOVEL GENE PRODUCTS","year":2002,"lang":"en","type":"review","venue":"Journal of Liposome Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transfection; Antigen; Immune system; Cytotoxic T cell; Liposome; Transgene; Genetic enhancement; Antibody; Immunology; Biology; Gene; Virology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004515389,0.0007056833,0.0008515112,0.0009447744,0.000192104,0.0006461131,0.0007603815,0.001028509,0.00166106],"category_scores_gemma":[0.0003364928,0.000160195,0.0002099778,0.0006099284,0.0004164466,0.0006862316,0.000328861,0.0008093393,0.002237033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003832065,"about_ca_system_score_gemma":0.0003170125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002623589,"about_ca_topic_score_gemma":0.0005037292,"domain_scores_codex":[0.9998356,0.00002532594,0.00001570788,0.00002703831,0.00007535739,0.00002090599],"domain_scores_gemma":[0.9998877,0.00004570115,0.00001905725,0.000009251466,0.00002929267,0.000008977197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008647324,0.00008091739,0.0002507908,0.005029726,0.00004215141,0.0006170015,0.00007270501,0.0003840454,0.05041559,0.00653382,0.0079675,0.9285192],"study_design_scores_gemma":[0.00002641881,0.000225667,0.001084138,0.0007208753,0.00006144492,0.005291541,0.00006029164,0.000187227,0.03850451,0.002776639,0.9510425,0.00001866138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002213879,0.9894055,0.002807574,0.0003655265,0.0002387908,0.00001289469,0.00001561518,0.00005500345,0.004885368],"genre_scores_gemma":[0.01236741,0.9783262,0.002299347,0.0004258866,0.0001924948,0.00003294963,0.00005462535,0.000008039891,0.006292936],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00166106,"threshold_uncertainty_score":0.005556822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2571591125865536,"score_gpt":0.4457294027707613,"score_spread":0.1885702901842077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}