{"id":"W2145044998","doi":"10.1081/lpr-120004793","title":"AVOIDING UNTOWARD IMMUNE RESPONSES TO NOVEL GENE PRODUCTS","year":2002,"lang":"en","type":"review","venue":"Journal of Liposome Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transfection; Antigen; Immune system; Cytotoxic T cell; Liposome; Transgene; Genetic enhancement; Antibody; Immunology; Biology; Gene; Virology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004505293,0.0003550911,0.001206584,0.0009864618,0.000232347,0.0001363391,0.001265544,0.0004217275,0.00005784353],"category_scores_gemma":[0.003020485,0.0002727394,0.0005881037,0.0007473991,0.0001085621,0.00001191432,0.000544293,0.001648469,0.0002783134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001385152,"about_ca_system_score_gemma":0.001075279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007411001,"about_ca_topic_score_gemma":0.000001193428,"domain_scores_codex":[0.9958539,0.0009838707,0.001114694,0.0004914956,0.0009003457,0.0006556974],"domain_scores_gemma":[0.9968101,0.0001945161,0.0004682927,0.0006870552,0.001552622,0.0002874091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004707745,0.0004757147,0.000004059792,0.004376284,0.0009432946,0.0002740326,0.0001418385,0.00000521565,0.3515321,0.000009099907,0.01978317,0.6219844],"study_design_scores_gemma":[0.0002415368,0.001418703,0.00000521706,0.004987871,0.0001016104,0.001360661,0.00004568069,4.643801e-7,0.02893536,0.000003957295,0.9626171,0.0002818197],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006527581,0.9920217,0.00006990862,0.000242427,0.0004668022,0.000450588,0.00004146339,0.000003630801,0.0001758922],"genre_scores_gemma":[0.001262591,0.9882204,0.00068,0.00002803161,0.00249181,0.00002377908,0.0000234225,0.00007409081,0.007195868],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.942834,"threshold_uncertainty_score":0.9999725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2571591125865536,"score_gpt":0.4457294027707613,"score_spread":0.1885702901842077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}