{"id":"W2145082934","doi":"10.1124/mol.105.012187","title":"Uridine Binding and Transportability Determinants of Human Concentrative Nucleoside Transporters","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside; Pyrimidine; Nucleoside analogue; Chemistry; Transporter; Xenopus; Biochemistry; Uridine; Cytidine; Biology; Biophysics; RNA; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001448229,0.000135817,0.0002092435,0.0001745525,0.0001947169,0.0004189003,0.0001971863,0.0002740353,0.002409533],"category_scores_gemma":[0.0004662313,0.0001502335,0.0001469819,0.0001614563,0.0001895972,0.0002173742,0.0001411635,0.0003517309,0.0005187814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000361559,"about_ca_system_score_gemma":0.0001583121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001571897,"about_ca_topic_score_gemma":0.001564878,"domain_scores_codex":[0.9998902,0.00003016481,0.000006744364,0.00002680655,0.0000200459,0.00002597888],"domain_scores_gemma":[0.9996855,0.0001563426,0.00004233891,0.0000251396,0.00003008088,0.00006066591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000361989,0.00003859044,0.001073538,0.00001434341,0.00000609352,0.0001109732,0.00005515219,0.0001556603,0.9951026,0.00119157,0.00005899539,0.001830458],"study_design_scores_gemma":[0.00003780243,0.0004041973,0.05210456,0.00001344154,0.00002472316,0.001576546,0.0001466239,0.005986315,0.9344423,0.0008317487,0.004407004,0.0000247308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995804,0.0004565289,0.00210811,0.00006506508,0.000008099059,0.00001030567,0.0001566861,0.00001359098,0.00137757],"genre_scores_gemma":[0.9972762,0.0002325825,0.001115922,0.00004005845,0.00001005144,0.000008397397,0.0003495374,0.0000139848,0.0009531452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002409533,"threshold_uncertainty_score":0.008060753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010912530189261,"score_gpt":0.2965108122418741,"score_spread":0.2864016869399815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}