{"id":"W2145137218","doi":"10.1086/520597","title":"Analysis of Filovirus Entry into Vero E6 Cells, Using Inhibitors of Endocytosis, Endosomal Acidification, Structural Integrity, and Cathepsin (B and L) Activity","year":2007,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Public Health Agency; Public Health Agency of Canada","keywords":"Endocytosis; Vero cell; Viral entry; Endosome; Biology; Proteases; Clathrin; Glycoprotein; Endocytic cycle; Receptor-mediated endocytosis; Virology; Cell biology; Receptor; Molecular biology; Virus; Biochemistry; Viral replication; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002384023,0.0004575405,0.0005101779,0.0002298834,0.0002685527,0.0005505562,0.0002486804,0.0004149778,0.0009113472],"category_scores_gemma":[0.0002298648,0.0001561231,0.0004277154,0.0002879833,0.0002667875,0.000359369,0.0001461534,0.0007913317,0.0002905584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004948206,"about_ca_system_score_gemma":0.0002580236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001538672,"about_ca_topic_score_gemma":0.002006582,"domain_scores_codex":[0.9996871,0.00006407692,0.00004070177,0.0000488378,0.00009008914,0.00006916576],"domain_scores_gemma":[0.9997397,0.0001425142,0.00003933539,0.00002939302,0.00002529876,0.00002374395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001426016,0.0000439749,0.0001652427,0.00003642944,0.000005844133,0.00003570885,0.00001845643,0.00004057034,0.9990062,0.00005082899,0.00001252869,0.0004416378],"study_design_scores_gemma":[0.00001302545,0.000376591,0.003801796,0.000003777806,0.00001447495,0.0001605322,0.00003011977,0.0008923274,0.9939427,0.00002851155,0.0007305575,0.000005663796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894855,0.002934341,0.004685546,0.00008393521,0.00005754798,0.00007093052,0.0008626219,0.00005068711,0.001768912],"genre_scores_gemma":[0.9820995,0.00257046,0.0100183,0.00006339313,0.00002528858,0.0000910083,0.002434841,0.00003967181,0.002657492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538672,"threshold_uncertainty_score":0.003590226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945223264494122,"score_gpt":0.3283283044330795,"score_spread":0.3088760717881383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}