{"id":"W2145146460","doi":"10.1016/j.joca.2003.09.014","title":"Rationale for the use of structure-modifying drugs and agents in the treatment of osteoarthritis","year":2003,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Osteoarthritis; Medicine; Disease; Cartilage; Pathophysiology; Chondrocyte; Bioinformatics; Synovial membrane; Inflammation; Immunology; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007595479,0.001005837,0.001632215,0.001709104,0.001804591,0.002124511,0.002789376,0.0089581,0.006662538],"category_scores_gemma":[0.006936654,0.0007198605,0.001710318,0.0007502528,0.00779664,0.001876215,0.001934655,0.01347376,0.002321862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002308868,"about_ca_system_score_gemma":0.004694151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001305844,"about_ca_topic_score_gemma":0.00300355,"domain_scores_codex":[0.9964736,0.001044886,0.0005590392,0.0005349818,0.00114308,0.0002443665],"domain_scores_gemma":[0.9957227,0.002256867,0.000475319,0.000205393,0.0008825538,0.0004572764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.004283929,0.002771343,0.005899333,0.006645921,0.0003556274,0.005443188,0.001075518,0.001469751,0.02184031,0.6222963,0.08020157,0.2477172],"study_design_scores_gemma":[0.004455875,0.003886533,0.007066235,0.005315193,0.0006080021,0.007643847,0.0005555223,0.001699695,0.008845337,0.1705711,0.789044,0.0003086985],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.02306811,0.3744114,0.026195,0.4784655,0.02937173,0.001053839,0.0008343614,0.0002433379,0.06635677],"genre_scores_gemma":[0.3339774,0.2635746,0.07319172,0.23521,0.05485606,0.003151932,0.0006764829,0.0001433745,0.03521842],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0089581,"threshold_uncertainty_score":0.04016924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03435792169368317,"score_gpt":0.2678480056560827,"score_spread":0.2334900839623996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}