{"id":"W2145173412","doi":"10.3747/co.21.2241","title":"Management of Diarrhea Induced by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors","year":2014,"lang":"en","type":"article","venue":"Current Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; Université de Montréal; McGill University Health Centre","funders":"","keywords":"Medicine; Erlotinib; Gefitinib; Afatinib; Epidermal growth factor receptor; Rash; Diarrhea; Tyrosine kinase; ErbB; Adverse effect; ERBB3; Epidermal growth factor; Tyrosine-kinase inhibitor; Pharmacology; Oncology; Internal medicine; Cancer; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002920617,0.0002184698,0.0005575343,0.0003356263,0.0004166182,0.00032672,0.0002387975,0.0004447741,0.0007609341],"category_scores_gemma":[0.0007154588,0.00007159651,0.0003103731,0.0002155413,0.000148981,0.0004023191,0.0004480972,0.001027867,0.0002545956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003138228,"about_ca_system_score_gemma":0.0002849629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003145843,"about_ca_topic_score_gemma":0.0007846435,"domain_scores_codex":[0.9998459,0.00005033114,0.00002428694,0.0000097115,0.00002974225,0.00003992296],"domain_scores_gemma":[0.9998079,0.00003662221,0.00006184889,0.000007847905,0.00003406921,0.00005175994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001611513,0.001203149,0.03042423,0.001918142,0.000208709,0.03675253,0.0003028944,0.001307893,0.03270993,0.002349966,0.02616202,0.8650489],"study_design_scores_gemma":[0.0023875,0.02009365,0.1963802,0.003822732,0.0007443769,0.2587446,0.001791047,0.01226815,0.0779883,0.009501117,0.4161325,0.000145956],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.692811,0.1738216,0.04563412,0.02719978,0.001538479,0.001105944,0.000292789,0.001263436,0.05633284],"genre_scores_gemma":[0.9293934,0.04624382,0.01005108,0.006160641,0.0008225706,0.0001366527,0.0002287612,0.00004153682,0.006921579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007609341,"threshold_uncertainty_score":0.002545595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04519274362707493,"score_gpt":0.389355629741363,"score_spread":0.3441628861142881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}