{"id":"W2145188829","doi":"10.1242/dev.096511","title":"The imprinted polycomb group gene <i>Sfmbt2</i> is required for trophoblast maintenance and placenta development","year":2013,"lang":"en","type":"article","venue":"Development","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences","keywords":"Trophoblast; Biology; Genomic imprinting; Placenta; Inner cell mass; Embryonic stem cell; Embryo; Embryogenesis; Gene; Genetics; Imprinting (psychology); Parthenogenesis; Allele; Cell biology; Stem cell; Blastocyst; Gene expression; DNA methylation; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007215966,0.000296138,0.0001880592,0.000306708,0.0001859015,0.0002706218,0.000170632,0.0001989988,0.00131149],"category_scores_gemma":[0.0001824849,0.0001377077,0.0001756425,0.0001903175,0.0002993676,0.0001383939,0.0002467059,0.0003039725,0.0003343548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002365274,"about_ca_system_score_gemma":0.000225042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593353,"about_ca_topic_score_gemma":0.002287716,"domain_scores_codex":[0.9998814,0.00001394281,0.00001254375,0.00002613642,0.00004360366,0.00002239653],"domain_scores_gemma":[0.9998398,0.00002094191,0.00005808882,0.00001812617,0.000009579004,0.00005348388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004300441,0.000002855855,0.0009280362,0.00001913284,0.000004928883,0.0002040735,0.00001377127,0.00003110445,0.997121,0.0001281741,0.00004375663,0.001460208],"study_design_scores_gemma":[0.00001629643,0.00006544578,0.05417746,0.000007618304,0.00002272777,0.002508267,0.00003080676,0.000834732,0.9368688,0.0001224282,0.005338567,0.000006810617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893076,0.001782434,0.005685749,0.0001180433,0.00002438077,0.00001137266,0.000859233,0.0001898513,0.002021335],"genre_scores_gemma":[0.9954432,0.0004530454,0.001337172,0.00002248019,0.000006739742,0.000009320137,0.000734968,0.0000283363,0.001964648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593353,"threshold_uncertainty_score":0.004387319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008274921547472978,"score_gpt":0.2090261805351666,"score_spread":0.2007512589876936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}