{"id":"W2145188829","doi":"10.1242/dev.096511","title":"The imprinted polycomb group gene <i>Sfmbt2</i> is required for trophoblast maintenance and placenta development","year":2013,"lang":"en","type":"article","venue":"Development","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences","keywords":"Trophoblast; Biology; Genomic imprinting; Placenta; Inner cell mass; Embryonic stem cell; Embryo; Embryogenesis; Gene; Genetics; Imprinting (psychology); Parthenogenesis; Allele; Cell biology; Stem cell; Blastocyst; Gene expression; DNA methylation; Fetus; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002305567,0.0002241229,0.0001506877,0.00002468726,0.0003902002,0.00009704744,0.000247014,0.00009257289,0.00002255659],"category_scores_gemma":[0.00004037807,0.0001664922,0.00004984444,0.000054454,0.00007011159,0.00000474077,0.0003154422,0.0000562217,0.00003185809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004182698,"about_ca_system_score_gemma":0.0001266582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001469914,"about_ca_topic_score_gemma":0.00002199804,"domain_scores_codex":[0.9985034,0.00001928663,0.0003853859,0.0004396792,0.0001425635,0.0005096226],"domain_scores_gemma":[0.9993513,0.00002058516,0.0001111475,0.000283813,0.0001044918,0.000128721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004260838,0.00005360337,0.002607385,0.00004142675,0.0002101358,7.856627e-7,0.0008434739,0.00000136304,0.8511358,0.00004802472,0.01204805,0.1329673],"study_design_scores_gemma":[0.0008994778,0.00009332343,0.05757776,0.00002459259,0.000006013826,0.00003398565,0.000285156,0.00007887493,0.5218405,0.00003432619,0.4188258,0.0003001271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905065,0.0006447577,0.00717182,0.0005096544,0.0002384987,0.0006893338,0.000003830701,0.00001447309,0.0002211478],"genre_scores_gemma":[0.9532328,0.0002685034,0.04145161,0.0007836858,0.00007201466,0.0004519586,0.00006214449,0.00003990069,0.003637387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4067778,"threshold_uncertainty_score":0.6789356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008274921547472978,"score_gpt":0.2090261805351666,"score_spread":0.2007512589876936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}