{"id":"W2145242994","doi":"10.1161/01.hyp.0000102863.23854.0b","title":"Aldosterone Increases NHE-1 Expression and Induces NHE-1-Dependent Hypertrophy in Neonatal Rat Ventricular Myocytes","year":2003,"lang":"en","type":"article","venue":"Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Merck KGaA; Heart and Stroke Foundation of Canada","keywords":"Aldosterone; Internal medicine; Endocrinology; Spironolactone; Muscle hypertrophy; Atrial natriuretic peptide; Mineralocorticoid receptor; Myocyte; Mineralocorticoid; Chemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685925,0.0002182585,0.0003608794,0.0001419681,0.0001369985,0.0001741367,0.0001056879,0.0001331852,0.001169762],"category_scores_gemma":[0.0001952568,0.0001551925,0.0002229246,0.0001088845,0.0001947439,0.0002266216,0.000234734,0.0005666062,0.0003677802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012335,"about_ca_system_score_gemma":0.0001432922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005742881,"about_ca_topic_score_gemma":0.00150547,"domain_scores_codex":[0.9998103,0.00003144362,0.00002299306,0.00002700019,0.00006124606,0.00004704522],"domain_scores_gemma":[0.9998192,0.00004225175,0.00003849231,0.00002047003,0.00001864803,0.00006097065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001149961,0.00001368538,0.0002249894,0.00002651525,0.00000206774,0.00004344349,0.00002012144,0.000007763766,0.9988922,0.00001049596,0.00001661383,0.0006270953],"study_design_scores_gemma":[0.00004591512,0.001133408,0.04490983,0.00001233715,0.00002166518,0.0004254937,0.0001300245,0.0002896854,0.9513873,0.00007683779,0.001559665,0.00000785059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960442,0.002348508,0.0005992292,0.00009599062,0.00003228732,0.00000936957,0.0001844568,0.00002869909,0.0006573868],"genre_scores_gemma":[0.9941722,0.001914791,0.001293207,0.00008346385,0.00004800492,0.00003800733,0.0004554715,0.00001760661,0.001977256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001169762,"threshold_uncertainty_score":0.003913283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0223128851229317,"score_gpt":0.2334849942468626,"score_spread":0.2111721091239309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}