{"id":"W2145264070","doi":"10.1016/j.biopsych.2009.04.002","title":"Identification and Characterization of Spermidine/Spermine N1-Acetyltransferase Promoter Variants in Suicide Completers","year":2009,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Genetics; Haplotype; Reporter gene; Biology; Single-nucleotide polymorphism; Gene; Acetyltransferase; Promoter; Molecular biology; Gene expression; Allele; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002664108,0.0005434067,0.0005219966,0.0005969845,0.0002263336,0.0004343944,0.0005388298,0.0004712741,0.00201272],"category_scores_gemma":[0.0006429884,0.0003185807,0.001007945,0.0003381431,0.0004129904,0.0001486897,0.0004318077,0.001109418,0.001041559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003751001,"about_ca_system_score_gemma":0.0002425162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001887073,"about_ca_topic_score_gemma":0.002505719,"domain_scores_codex":[0.9996529,0.00004929469,0.00005398345,0.00008402432,0.0001013247,0.00005860022],"domain_scores_gemma":[0.9993443,0.0001832771,0.0002073794,0.000085656,0.00008472575,0.00009470618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001004989,0.00004851338,0.0009330839,0.00003390405,0.00003883614,0.0003604519,0.00008747536,0.0001275942,0.9957719,0.000163696,0.00006674377,0.002267183],"study_design_scores_gemma":[0.00006930669,0.0003809208,0.02362637,0.00003345606,0.0001912811,0.003935804,0.0002372413,0.003286853,0.9632833,0.0001808474,0.004730434,0.00004410879],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790837,0.000398371,0.01670107,0.0001291314,0.00006045919,0.0001329138,0.002355055,0.0002070175,0.0009323829],"genre_scores_gemma":[0.9875546,0.0002913864,0.005193219,0.00008864055,0.00001828261,0.00008012911,0.003687996,0.0003213112,0.002764427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00201272,"threshold_uncertainty_score":0.006733239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01781680825358289,"score_gpt":0.2684382215096149,"score_spread":0.250621413256032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}