{"id":"W2145264070","doi":"10.1016/j.biopsych.2009.04.002","title":"Identification and Characterization of Spermidine/Spermine N1-Acetyltransferase Promoter Variants in Suicide Completers","year":2009,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Genetics; Haplotype; Reporter gene; Biology; Single-nucleotide polymorphism; Gene; Acetyltransferase; Promoter; Molecular biology; Gene expression; Allele; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001088342,0.0001044442,0.0001413283,0.00003986697,0.0000275253,0.000008791299,0.0001024969,0.0001116085,0.00001137553],"category_scores_gemma":[0.0000168072,0.00008567257,0.00003692826,0.0001039445,0.00006213055,0.000005278187,0.00001648313,0.00004819359,0.000002534935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002554985,"about_ca_system_score_gemma":0.00001548638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004315753,"about_ca_topic_score_gemma":0.000005068728,"domain_scores_codex":[0.9992375,0.00004230017,0.0002739675,0.0002708354,0.00004499945,0.0001303323],"domain_scores_gemma":[0.9996755,0.000003605764,0.00006712196,0.0001873603,0.00002179963,0.00004458617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004747495,0.000161283,0.02228299,0.000006323319,0.000004061516,2.051608e-7,0.00000974505,4.343017e-7,0.9738449,0.0009409321,0.0000180192,0.002683596],"study_design_scores_gemma":[0.0004373611,0.0001776751,0.91567,0.00001051822,0.000006729313,0.000006953293,0.000009329443,0.00003401169,0.08241071,0.0005221516,0.0005960315,0.0001185059],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964897,0.0002176851,0.00177204,0.001036941,0.00008457227,0.0002443457,0.00006650424,0.000008630141,0.00007956831],"genre_scores_gemma":[0.9983141,0.0002991827,0.0004237826,0.0003665923,0.000124684,0.0000125159,0.0004136001,0.000004747978,0.00004074461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.893387,"threshold_uncertainty_score":0.3493626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01781680825358289,"score_gpt":0.2684382215096149,"score_spread":0.250621413256032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}