{"id":"W2145287700","doi":"10.1016/j.nbd.2011.06.007","title":"Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme","year":2011,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Toronto Western Hospital; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Glioblastoma; Glycolysis; Hexokinase; Enzyme; Neuroscience; Human brain; Biology; Cancer research; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268415,0.0001285284,0.0002480619,0.0007365973,0.000228875,0.0004782595,0.0001874856,0.0001736092,0.0009017122],"category_scores_gemma":[0.00025073,0.000235348,0.0001432869,0.0002805087,0.0002684795,0.0002310987,0.0002588434,0.0003167861,0.0002243708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006746134,"about_ca_system_score_gemma":0.0004163168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00439938,"about_ca_topic_score_gemma":0.005505461,"domain_scores_codex":[0.9999057,0.00001247608,0.000008252902,0.00002003742,0.00002360073,0.0000299594],"domain_scores_gemma":[0.999848,0.00002414818,0.00004653286,0.000009275587,0.00003084832,0.00004118751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00113938,0.00003639173,0.007047486,0.00004356538,0.00001978016,0.0003688564,0.000151357,0.0001200243,0.982981,0.00115141,0.0002596947,0.00668108],"study_design_scores_gemma":[0.00004587556,0.000430983,0.4095125,0.0000263044,0.0000768208,0.001842015,0.000677079,0.001411302,0.5737203,0.0008837612,0.01134438,0.00002855343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923199,0.003763934,0.001454675,0.0001121469,0.00002281136,0.0000104675,0.0005929309,0.00003378388,0.001689228],"genre_scores_gemma":[0.9940659,0.001713336,0.0007483545,0.00006273322,0.000007599958,0.00001763831,0.0005965122,0.00002527412,0.002762612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00439938,"threshold_uncertainty_score":0.008747578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007486622822498087,"score_gpt":0.2020806018723667,"score_spread":0.1945939790498686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}