{"id":"W2145315186","doi":"10.1146/annurev.pharmtox.42.091601.142813","title":"Glycopeptide Antibiotic Resistance","year":2002,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Glycopeptide; Antibiotics; Antibiotic resistance; Microbiology; Virulence; Biology; Bacteria; Glycopeptide antibiotic; Gene; Computational biology; Vancomycin; Staphylococcus aureus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008975571,0.000556701,0.004068541,0.0001623612,0.0001390411,0.000005257125,0.0004973859,0.0004929146,0.001006437],"category_scores_gemma":[0.0003481107,0.0003411668,0.0006591029,0.0005366328,0.001307995,0.00005602966,0.0002428339,0.001026563,0.0001835829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008880325,"about_ca_system_score_gemma":0.0003542836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002046975,"about_ca_topic_score_gemma":0.000004351235,"domain_scores_codex":[0.9965328,0.0008633471,0.0012946,0.0005739538,0.0001957791,0.000539493],"domain_scores_gemma":[0.9971002,0.001005333,0.0009998269,0.0005132627,0.0002421751,0.0001391974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000861462,0.00019404,0.000001830831,0.3212758,0.0006613205,0.0002079368,0.00004090219,1.337513e-8,0.00004123204,0.0005176007,0.2381593,0.4388139],"study_design_scores_gemma":[0.0004086632,0.0002483951,0.000006560171,0.0861842,0.006255777,0.0004405417,0.00001015982,1.486137e-7,0.00002606816,0.00001725476,0.906166,0.0002362984],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000009661432,0.9870104,0.000003231913,0.002073758,0.0004689483,0.002577777,0.0001795572,0.00003525914,0.007641437],"genre_scores_gemma":[0.00003479782,0.987967,0.0001442487,0.006046537,0.0003068549,0.0000794319,0.00003333685,0.00005804316,0.005329766],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6680067,"threshold_uncertainty_score":0.9999068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03333524559854153,"score_gpt":0.3797161555212049,"score_spread":0.3463809099226634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}