{"id":"W2145328346","doi":"10.1093/toxsci/59.1.82","title":"Strain-Related Differences in Bioactivation of Vinyl Carbamate and Formation of DNA Adducts in Lungs of A/J, CD-1, and C57BL/6 Mice","year":2001,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute; University of Toronto","keywords":"Carboxylesterase; Chemistry; Molecular biology; Adduct; DNA; Carcinogen; Enzyme; Strain (injury); Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000561157,0.001060216,0.000515984,0.001992445,0.0003191385,0.0005736309,0.000417148,0.0008379339,0.001943507],"category_scores_gemma":[0.0004840276,0.0005624308,0.0005477476,0.0003261151,0.0006252722,0.0005350222,0.0003813284,0.001349055,0.0005133648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004244484,"about_ca_system_score_gemma":0.0002024954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009084528,"about_ca_topic_score_gemma":0.001531564,"domain_scores_codex":[0.9990368,0.0001462983,0.0001093919,0.0003178582,0.000195779,0.0001938854],"domain_scores_gemma":[0.9986123,0.0001636245,0.0005352118,0.0001185149,0.0001331449,0.000437189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006253577,0.000203714,0.001329576,0.00001986191,0.00001684606,0.00004088007,0.00003492259,0.00002533588,0.9971594,0.00005627784,0.00001878889,0.00046907],"study_design_scores_gemma":[0.0001782033,0.006198439,0.1197375,0.00002435403,0.0002076273,0.001320556,0.0002560877,0.00102809,0.8696916,0.0002095893,0.001099056,0.00004884639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997431,0.0006166073,0.0008785129,0.00005263555,0.00002028345,0.00003256257,0.0004291503,0.00004223517,0.0004968822],"genre_scores_gemma":[0.9919032,0.0007470534,0.002319228,0.0001580521,0.00002308335,0.0001452855,0.001346772,0.00006990987,0.003287411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001992445,"threshold_uncertainty_score":0.006501675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02463498639926484,"score_gpt":0.2694849354836205,"score_spread":0.2448499490843556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}