{"id":"W2145332276","doi":"10.1164/rccm.201412-2326oc","title":"Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway","year":2015,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"ARDS; Medicine; Lung; Pulmonary fibrosis; Fibrosis; Midkine; Oxidative stress; Idiopathic pulmonary fibrosis; Endocrinology; Immunology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273464,0.0003438173,0.0001760839,0.0001791398,0.0001282958,0.0002624089,0.0001298489,0.0003025404,0.001342887],"category_scores_gemma":[0.0001222325,0.000101294,0.000193887,0.00007006246,0.0002723124,0.0001589117,0.000331576,0.0004962648,0.0001779927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002075025,"about_ca_system_score_gemma":0.0001536517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000109951,"about_ca_topic_score_gemma":0.0001780114,"domain_scores_codex":[0.9998888,0.00002503856,0.00001111593,0.00001759873,0.00003067057,0.00002687345],"domain_scores_gemma":[0.9998657,0.00001568377,0.00006512381,0.000006980741,0.00001099803,0.00003557875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001127485,0.0001840272,0.00556584,0.0002342792,0.00002246192,0.0003470935,0.00003105511,0.00008425346,0.9873986,0.0001642031,0.0001276668,0.004712922],"study_design_scores_gemma":[0.0003553917,0.007878847,0.4129983,0.0001539413,0.0001284321,0.004632513,0.0003555817,0.002552951,0.5644253,0.0006498517,0.005835545,0.00003331485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914134,0.005871193,0.001209558,0.000270762,0.00003921913,0.00005446071,0.000231625,0.00002552712,0.0008843978],"genre_scores_gemma":[0.9967723,0.001696218,0.0006463936,0.000105404,0.00002939307,0.00006474365,0.0001559154,0.000001760832,0.0005278353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001342887,"threshold_uncertainty_score":0.004492402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04888577823373448,"score_gpt":0.3733582773061853,"score_spread":0.3244724990724508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}