{"id":"W2145352784","doi":"10.1093/carcin/bgn073","title":"Genetic variations of microRNAs in human cancer and their effects on the expression of miRNAs","year":2008,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute; McGill University","funders":"Medical Research Council; Wellcome Trust","keywords":"microRNA; Biology; Carcinogenesis; Gene; Genetics; Mutation; Single-nucleotide polymorphism; Gene expression; Computational biology; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005435047,0.00008681913,0.0001104091,0.00004417172,0.00005294435,0.000001649936,0.00009003813,0.00006645217,0.000007901554],"category_scores_gemma":[0.00002804742,0.00006162973,0.00004891355,0.00007376375,0.00007607252,0.000001279661,0.00004498281,0.00002360177,2.250047e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000103019,"about_ca_system_score_gemma":0.00003811427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007132002,"about_ca_topic_score_gemma":0.00002258579,"domain_scores_codex":[0.9994798,0.00007284223,0.0001503726,0.0001553432,0.00005631565,0.00008538119],"domain_scores_gemma":[0.9995522,0.00003264051,0.00009007881,0.0002507999,0.00004875421,0.00002546877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002059112,0.00002986734,0.06685008,0.0000399655,0.00001321464,6.457554e-7,0.0001417409,0.00007525129,0.932353,0.00002148239,0.0001084941,0.0003457237],"study_design_scores_gemma":[0.0001601475,0.00003091572,0.3997614,0.00002873719,0.000006786532,0.000001553326,0.000009131307,0.000008445822,0.5998865,0.00002244606,0.00004669886,0.00003727817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963722,0.003210952,0.00009796434,0.00003826944,0.00002496921,0.0001927454,0.00002088736,0.00000186737,0.0000401822],"genre_scores_gemma":[0.9995336,0.0002173259,0.00008761372,0.00003578319,0.00004559288,0.00003572392,0.00001037758,0.00001134138,0.00002265328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3329113,"threshold_uncertainty_score":0.2513187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01324877949970062,"score_gpt":0.2355657383090052,"score_spread":0.2223169588093045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}