{"id":"W2145430092","doi":"10.4049/jimmunol.0801199","title":"The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Pfizer","keywords":"Pneumococcal pneumonia; Glycation; Pneumonia; Host (biology); Receptor; Immunology; Microbiology; Streptococcus pneumoniae; Medicine; Biology; Internal medicine; Ecology; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004549125,0.0005521346,0.0005890707,0.000187856,0.0001059204,0.0002405075,0.0002604969,0.0006448983,0.001932868],"category_scores_gemma":[0.0002686408,0.0001610143,0.0002840954,0.0001479104,0.0002650569,0.000277271,0.000263734,0.0008639902,0.0005576182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001462071,"about_ca_system_score_gemma":0.0001665676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001868039,"about_ca_topic_score_gemma":0.0001592014,"domain_scores_codex":[0.9996598,0.0001102087,0.00002984989,0.00003588085,0.00008432617,0.00008002304],"domain_scores_gemma":[0.9998486,0.00001969502,0.00003709887,0.00002005243,0.00001786768,0.00005666448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001350871,0.000345895,0.0005525288,0.0001626205,0.00003105532,0.0003221652,0.00001898408,0.00009707079,0.9896101,0.0001752003,0.0002196333,0.007113951],"study_design_scores_gemma":[0.0004983866,0.01554418,0.06169379,0.00006329601,0.0002027428,0.004125211,0.00009518336,0.001841998,0.8982617,0.0004618721,0.01717507,0.00003666497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797987,0.01308609,0.00266016,0.0004122298,0.0002842836,0.0001088964,0.0004116052,0.0001458522,0.003092217],"genre_scores_gemma":[0.9894874,0.004101401,0.001295223,0.0002457354,0.00007777247,0.00009507007,0.0004837701,0.00001578607,0.004197767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001932868,"threshold_uncertainty_score":0.006466031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01061625527515165,"score_gpt":0.286790403397732,"score_spread":0.2761741481225804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}