{"id":"W2145500184","doi":"10.1093/glycob/cwl026","title":"Exo-β-d-glucosaminidase from Amycolatopsis orientalis: catalytic residues, sugar recognition specificity, kinetics, and synergism","year":2006,"lang":"en","type":"article","venue":"Glycobiology","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Chemistry; Hydrolysis; Enzyme; Disaccharide; Residue (chemistry); Stereochemistry; Oligosaccharide; Glycoside hydrolase; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008034292,0.0001743777,0.0001631655,0.00005672856,0.00007565664,0.00002908081,0.00009532089,0.0002445864,0.00009147829],"category_scores_gemma":[0.00005743406,0.0001767628,0.00004300141,0.00008054241,0.0001447671,0.000007583883,0.00009371402,0.00008406949,0.00004798388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001847606,"about_ca_system_score_gemma":0.0000182642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003435799,"about_ca_topic_score_gemma":0.0004079739,"domain_scores_codex":[0.998844,0.00008363366,0.0002657925,0.0005263234,0.00006170101,0.0002185265],"domain_scores_gemma":[0.9994521,0.00001561279,0.0001125458,0.0002851235,0.00007586065,0.00005876726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001080459,0.00009534104,0.006535238,0.000008776291,0.00002607326,0.000005820055,0.00002103061,0.000002372264,0.9867336,0.0001415786,0.004395734,0.001926345],"study_design_scores_gemma":[0.0007664704,0.000272466,0.06309421,0.0000137452,0.00004555647,0.00006403754,0.00006891579,0.00001115368,0.8511497,0.0009387588,0.08322428,0.0003507484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996717,0.0007400043,0.000359168,0.0002655798,0.0005551527,0.0001512524,0.0002532212,0.00003512518,0.0009234332],"genre_scores_gemma":[0.9881382,0.000333871,0.0004452551,0.0002588817,0.001127767,0.00001811375,0.008988163,0.00002302619,0.000666737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.135584,"threshold_uncertainty_score":0.7208178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008839098762062614,"score_gpt":0.2083853346631663,"score_spread":0.1995462359011037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}