{"id":"W2145500610","doi":"10.1002/gcc.10117","title":"Molecular cytogenetics of the acute promyelocytic leukemia‐derived cell line NB4 and of four all‐trans retinoic acid–resistant subclones","year":2002,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Acute promyelocytic leukemia; Retinoic acid; Biology; Cell culture; Molecular biology; Fusion gene; Cancer research; Chromosomal translocation; Leukemia; Promyelocytic leukemia protein; Retinoic acid receptor alpha; Cytogenetics; Retinoid; Molecular cytogenetics; Gene; Genetics; Retinoic acid receptor; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001835335,0.0004107013,0.0002878518,0.000957829,0.0003601877,0.0003110423,0.0003456517,0.0002762727,0.002972081],"category_scores_gemma":[0.0002714153,0.0002019154,0.000314614,0.0003610112,0.0003468086,0.000170498,0.0004170443,0.0003876645,0.0008436767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005014971,"about_ca_system_score_gemma":0.000309055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004031063,"about_ca_topic_score_gemma":0.002541992,"domain_scores_codex":[0.9997615,0.00003689538,0.00003405431,0.00005892323,0.00008023974,0.00002835638],"domain_scores_gemma":[0.9998336,0.00003179396,0.00002320776,0.00004049906,0.00004366741,0.00002723427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001346982,0.00001812268,0.001920596,0.00002823112,0.000009486239,0.00008437417,0.00005275888,0.0001225797,0.9947181,0.0002199849,0.00007164069,0.002619375],"study_design_scores_gemma":[0.0001403068,0.001095836,0.1240409,0.00003342611,0.0001534205,0.003167226,0.0004454156,0.003325346,0.834711,0.0005452505,0.03229695,0.00004502699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796907,0.001352754,0.007892297,0.0001568751,0.00003466767,0.0001673144,0.003310327,0.0001796612,0.007215385],"genre_scores_gemma":[0.9665904,0.001490677,0.01199478,0.00005885758,0.00001098668,0.0003256852,0.009070906,0.00007747492,0.01038016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004031063,"threshold_uncertainty_score":0.009942532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128805151301546,"score_gpt":0.2256897631785101,"score_spread":0.2128092480483555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}