{"id":"W2145536439","doi":"10.7150/ijbs.5.171","title":"Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression","year":2009,"lang":"en","type":"article","venue":"International Journal of Biological Sciences","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Environmental Health Sciences; University of Toronto","keywords":"Transgene; Transactivation; Gene expression; Reporter gene; Doxycycline; Gene; Genetically modified mouse; Offspring; Biology; Pharmacology; Regulation of gene expression; Molecular biology; Chemistry; Genetics; Pregnancy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003827317,0.00005076535,0.00006601193,0.00003789259,0.00007053588,0.00002822657,0.0002060332,0.00005936022,0.000004191658],"category_scores_gemma":[0.00009419789,0.00003149886,0.00004892369,0.00004176086,0.000086363,0.000007672765,0.00002627604,0.00003356245,2.528421e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007522039,"about_ca_system_score_gemma":0.00004920354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.937798e-7,"about_ca_topic_score_gemma":4.328816e-7,"domain_scores_codex":[0.9994624,0.00001854548,0.000158059,0.0001605245,0.0001171898,0.00008329641],"domain_scores_gemma":[0.999657,0.0000101445,0.0001066353,0.00003120578,0.0001609888,0.00003403948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008028611,0.0000178426,0.001102304,5.606459e-7,0.000009043259,6.97639e-7,0.00001250193,0.00002746559,0.9904928,0.0002766216,0.0001265532,0.007853308],"study_design_scores_gemma":[0.0002141002,0.001064522,0.008473756,0.00001637403,0.000003220505,0.00006373824,0.00004472096,0.00001134077,0.9756367,0.002837063,0.01156552,0.00006899337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823273,0.0009247481,0.01429219,0.00205012,0.0002627436,0.00004590568,0.000002301165,0.000001511097,0.00009313725],"genre_scores_gemma":[0.9756445,0.001116711,0.02254395,0.0002386624,0.0004015278,6.617954e-7,0.000003051729,0.000001119624,0.00004983855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01485617,"threshold_uncertainty_score":0.1284486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07323868211280857,"score_gpt":0.3441731385028863,"score_spread":0.2709344563900777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}