{"id":"W2145536439","doi":"10.7150/ijbs.5.171","title":"Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression","year":2009,"lang":"en","type":"article","venue":"International Journal of Biological Sciences","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Environmental Health Sciences; University of Toronto","keywords":"Transgene; Transactivation; Gene expression; Reporter gene; Doxycycline; Gene; Genetically modified mouse; Offspring; Biology; Pharmacology; Regulation of gene expression; Molecular biology; Chemistry; Genetics; Pregnancy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004996593,0.001018375,0.0005798079,0.00113099,0.0003447058,0.0004599316,0.0009668395,0.0008293928,0.00470818],"category_scores_gemma":[0.0003498851,0.0006229999,0.0009100938,0.0003800151,0.0004337103,0.0005556546,0.0005464863,0.002055941,0.002262389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003937225,"about_ca_system_score_gemma":0.0005556743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008189385,"about_ca_topic_score_gemma":0.001297793,"domain_scores_codex":[0.9995179,0.00005404988,0.00005166642,0.0001320671,0.0001420501,0.000102196],"domain_scores_gemma":[0.9991984,0.00008585268,0.0002670848,0.0001139591,0.0001216167,0.0002131145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001120994,0.0001064094,0.0001732886,0.00004430207,0.00001191026,0.0001359597,0.0000381611,0.0001359231,0.9938903,0.0005323607,0.0001840792,0.004635159],"study_design_scores_gemma":[0.0001008926,0.001055003,0.001495317,0.0000287631,0.00005621659,0.000869826,0.00003423876,0.001688648,0.9828417,0.0002500261,0.01154794,0.00003144419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7707951,0.003878219,0.1995925,0.0006463445,0.0007044612,0.001316353,0.004946782,0.007288421,0.0108318],"genre_scores_gemma":[0.7384568,0.006153254,0.1850193,0.0004815292,0.0001723251,0.00316796,0.005709715,0.001539366,0.05929977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00470818,"threshold_uncertainty_score":0.01575041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07323868211280857,"score_gpt":0.3441731385028863,"score_spread":0.2709344563900777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}