{"id":"W2145604116","doi":"10.1002/ddr.10135","title":"Contribution of EDHF and the role of potassium channels in the regulation of vascular tone","year":2003,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Heart and Stroke Foundation of Canada","keywords":"Charybdotoxin; Apamin; Prostacyclin; Potassium channel; Endothelium-derived hyperpolarizing factor; Calcium-activated potassium channel; Chemistry; Endothelium; SK channel; Vascular smooth muscle; Vasodilation; Endothelial dysfunction; Nitric oxide; Pharmacology; Biophysics; Internal medicine; Biochemistry; Ion channel; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003585221,0.0002275976,0.0002645835,0.0002200637,0.0002250285,0.0005351872,0.0003030789,0.0005252015,0.001056742],"category_scores_gemma":[0.0004636114,0.00009338998,0.0002121425,0.0001007424,0.0003602085,0.0006001496,0.0003632268,0.0006765837,0.0001537054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000365159,"about_ca_system_score_gemma":0.0002683943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004963226,"about_ca_topic_score_gemma":0.0002811208,"domain_scores_codex":[0.9998469,0.00004364039,0.00001357979,0.00002129062,0.00003052692,0.00004400582],"domain_scores_gemma":[0.9996262,0.0001077256,0.00008153381,0.00002633084,0.00007856269,0.00007977607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006836585,0.0005773492,0.0158534,0.002184866,0.0002235342,0.0034535,0.0004121897,0.003066451,0.8249261,0.01652034,0.001830902,0.1241148],"study_design_scores_gemma":[0.001203932,0.008276681,0.4135187,0.001194729,0.0008121505,0.01361881,0.001939769,0.02524503,0.3957085,0.06326658,0.0749881,0.0002269865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.803656,0.172048,0.009212783,0.003939903,0.0007975353,0.00005046166,0.0002514546,0.00006561456,0.009978156],"genre_scores_gemma":[0.97003,0.02506198,0.001796232,0.0004034232,0.0004123061,0.00002113439,0.00004756636,0.0000062002,0.002221082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001056742,"threshold_uncertainty_score":0.003535092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01851268398416199,"score_gpt":0.3153485145311467,"score_spread":0.2968358305469847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}