{"id":"W2145636817","doi":"10.1091/mbc.e10-02-0160","title":"Selective Association of Peroxiredoxin 1 with Genomic DNA and <i>COX-2</i> Upstream Promoter Elements in Estrogen Receptor Negative Breast Cancer Cells","year":2010,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Biology; Estrogen receptor; Transactivation; Cancer research; Transcription factor; Cancer cell; Estrogen receptor alpha; Breast cancer; Molecular biology; Cancer; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001987641,0.0001690814,0.0002228719,0.00003802195,0.00003947448,0.000003157769,0.000227136,0.0002907183,0.00001802876],"category_scores_gemma":[0.00002935193,0.0001171454,0.00005903403,0.0000976492,0.0003084755,0.00000341242,0.0001286968,0.0001972869,9.395919e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002223823,"about_ca_system_score_gemma":0.00008922881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001109767,"about_ca_topic_score_gemma":0.000231505,"domain_scores_codex":[0.9989265,0.000226281,0.0002287209,0.0003331467,0.00006067161,0.0002246788],"domain_scores_gemma":[0.9992366,0.00002144726,0.000344265,0.0002425919,0.0001212999,0.00003381816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001631104,0.00007347875,0.1921553,0.00001431518,0.0001011226,2.84153e-7,0.00008041135,0.000007755189,0.8070769,0.00001541844,0.00004768715,0.0002642608],"study_design_scores_gemma":[0.0008338531,0.0002847683,0.03409791,0.00001400317,0.00003522324,0.000002975925,0.00003473826,0.000004235143,0.9643358,0.00009568212,0.0001381534,0.0001226295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986871,0.0001407376,0.00003876903,0.0001936717,0.0001137288,0.0003522963,0.000238631,0.000002569313,0.0002324848],"genre_scores_gemma":[0.998907,0.00007826254,0.0006661895,0.00007657148,0.00003297484,0.00003033421,0.00003841773,0.00001478445,0.0001554744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1580574,"threshold_uncertainty_score":0.4777052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001829015785633077,"score_gpt":0.2088032430782315,"score_spread":0.2069742272925985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}