{"id":"W2145636817","doi":"10.1091/mbc.e10-02-0160","title":"Selective Association of Peroxiredoxin 1 with Genomic DNA and <i>COX-2</i> Upstream Promoter Elements in Estrogen Receptor Negative Breast Cancer Cells","year":2010,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Biology; Estrogen receptor; Transactivation; Cancer research; Transcription factor; Cancer cell; Estrogen receptor alpha; Breast cancer; Molecular biology; Cancer; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063654,0.0002023836,0.0001877826,0.0001540935,0.0001238308,0.0002042703,0.0001089171,0.0001670314,0.00103815],"category_scores_gemma":[0.0001048389,0.0001694788,0.0001898693,0.000123376,0.0001425585,0.0001464472,0.0001543092,0.0003026394,0.0003113387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994296,"about_ca_system_score_gemma":0.0001059567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004592518,"about_ca_topic_score_gemma":0.0005446946,"domain_scores_codex":[0.9998783,0.00001293084,0.000007472913,0.00004590261,0.00003085472,0.00002450596],"domain_scores_gemma":[0.9999162,0.00001334169,0.00002468013,0.00001030713,0.00001396228,0.00002151992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004148861,0.000007942403,0.0003862527,0.00002152474,0.000002270208,0.00003246794,0.00001901174,0.000008636225,0.9990916,0.00002357092,0.00001432291,0.0003509521],"study_design_scores_gemma":[0.0000081137,0.0001803809,0.02252506,0.000004424154,0.00001257391,0.0005316978,0.00007698636,0.0003043407,0.9746146,0.00003281905,0.001705605,0.00000346455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943945,0.001823436,0.002756861,0.00007433634,0.00002048154,0.00001540838,0.000282509,0.00004190653,0.0005903999],"genre_scores_gemma":[0.9942839,0.0006325162,0.001851381,0.00005074286,0.000007817618,0.00002649804,0.000814657,0.000009755728,0.002322768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00103815,"threshold_uncertainty_score":0.003472984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001829015785633077,"score_gpt":0.2088032430782315,"score_spread":0.2069742272925985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}