{"id":"W2145708021","doi":"10.4049/jimmunol.171.6.3119","title":"Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance to <i>Bordetella pertussis</i> by Inhibiting Inflammatory Pathology","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":262,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Bordetella pertussis; TLR4; Immunology; Chemokine; Toll-like receptor; Cytokine; Biology; Innate immune system; Inflammation; Pertussis toxin; Cell biology; Immune system; Signal transduction; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002070529,0.0003307252,0.0006137635,0.0003277824,0.0004117479,0.00002786571,0.0004092832,0.0004797004,0.0004185595],"category_scores_gemma":[0.0004154511,0.000248605,0.0001104561,0.0002467282,0.0007050791,0.0002307751,0.0001078357,0.0008218985,0.0002922414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001008559,"about_ca_system_score_gemma":0.0001835254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003732514,"about_ca_topic_score_gemma":0.000003950235,"domain_scores_codex":[0.995964,0.002071732,0.001028584,0.0002562157,0.00008957706,0.0005898765],"domain_scores_gemma":[0.9974626,0.0008977002,0.0008554172,0.000386082,0.0003491488,0.00004908449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002518327,0.00004785636,0.00007916977,0.0000102022,0.0002450703,0.00001786978,0.001662669,0.000004432244,0.9694323,0.0002840456,0.02418329,0.001514755],"study_design_scores_gemma":[0.001056022,0.000264432,0.0007022299,0.00005725383,0.00001589213,0.0003551359,0.001062135,1.465905e-7,0.5898839,0.00003674533,0.4063955,0.0001705796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689497,0.02793612,0.00009079031,0.001153345,0.001120401,0.0002591114,0.00001818907,0.00003332041,0.0004389906],"genre_scores_gemma":[0.9845937,0.01210121,0.0001156446,0.000504463,0.00004066458,0.000007756766,0.00002160547,0.00004393569,0.002571023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3822122,"threshold_uncertainty_score":0.9999966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005651758071594857,"score_gpt":0.1940427342439803,"score_spread":0.1883909761723855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}