{"id":"W2145708021","doi":"10.4049/jimmunol.171.6.3119","title":"Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance to <i>Bordetella pertussis</i> by Inhibiting Inflammatory Pathology","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":262,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Bordetella pertussis; TLR4; Immunology; Chemokine; Toll-like receptor; Cytokine; Biology; Innate immune system; Inflammation; Pertussis toxin; Cell biology; Immune system; Signal transduction; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215539,0.0005500449,0.0003281091,0.0003151619,0.0001231791,0.0003136362,0.0002113912,0.0003595376,0.001467707],"category_scores_gemma":[0.00008998559,0.000192894,0.0002282423,0.00009075522,0.0003115055,0.0001418169,0.0001822863,0.0007736322,0.000535958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003035716,"about_ca_system_score_gemma":0.0002116693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004797148,"about_ca_topic_score_gemma":0.0007224394,"domain_scores_codex":[0.9998224,0.00003472153,0.00001140376,0.00002705668,0.00003245044,0.00007195052],"domain_scores_gemma":[0.9999086,0.00001117082,0.00003070782,0.00001189706,0.000007068871,0.00003055347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001045449,0.0000238244,0.0001613638,0.00001826893,0.00000244377,0.00003538155,0.00000338172,0.00002428246,0.9990773,0.00002849673,0.00002752852,0.0004931343],"study_design_scores_gemma":[0.00003333396,0.0004176965,0.007218732,0.000008135089,0.00001949447,0.0003956054,0.00002233222,0.0007684128,0.9893976,0.00005954423,0.001654822,0.000004178848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994674,0.001141514,0.001829785,0.0001503568,0.00003441348,0.00001805434,0.0002377258,0.0001606095,0.001753547],"genre_scores_gemma":[0.9941702,0.0007566796,0.001447862,0.00008742799,0.00001796613,0.00002089312,0.0003930414,0.00002465126,0.003081201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467707,"threshold_uncertainty_score":0.004909933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005651758071594857,"score_gpt":0.1940427342439803,"score_spread":0.1883909761723855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}