{"id":"W2145720279","doi":"10.4049/jimmunol.173.11.6727","title":"Individual Nonobese Diabetic Mice Exhibit Unique Patterns of CD8+ T Cell Reactivity to Three Islet Antigens, Including the Newly Identified Widely Expressed Dystrophia Myotonica Kinase","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Biology; CD8; NOD mice; Antigen; T cell; Islet; Molecular biology; CD28; Immunology; Antibody; Immune system; Autoimmunity; Endocrinology; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001695665,0.0004408237,0.0002965041,0.0007059519,0.0001399449,0.0003209885,0.0001570083,0.0002863704,0.0009930922],"category_scores_gemma":[0.0001569472,0.0002012694,0.0001771381,0.0002458298,0.0002116305,0.0001886335,0.000274761,0.0005051353,0.0003868981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339498,"about_ca_system_score_gemma":0.00006514927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000122844,"about_ca_topic_score_gemma":0.0002907094,"domain_scores_codex":[0.9997569,0.00002013693,0.00002497674,0.00008996647,0.00005662503,0.00005141067],"domain_scores_gemma":[0.9996883,0.00003332625,0.00008944172,0.00005377639,0.00002599447,0.0001091321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009167004,0.00004293879,0.004409523,0.00001279353,0.000008876804,0.00008029454,0.00002112654,0.00003231785,0.9935661,0.0000208874,0.00001778307,0.001695698],"study_design_scores_gemma":[0.00006542177,0.002023707,0.2761489,0.00001884355,0.0002127361,0.005158564,0.0002875006,0.001606137,0.711337,0.0003735248,0.002734159,0.00003344439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997622,0.0002413334,0.001021464,0.00001539192,0.000006217394,0.00001792743,0.0001747353,0.00005724294,0.0008437571],"genre_scores_gemma":[0.9953413,0.0003178492,0.002166497,0.00007136539,0.00001616483,0.00006023253,0.0004519443,0.00004377841,0.0015309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009930922,"threshold_uncertainty_score":0.003322244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194433879849787,"score_gpt":0.234215601939667,"score_spread":0.2222712631411691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}