{"id":"W2145736208","doi":"10.1128/aac.00100-13","title":"Characterization of Antiviral Activity of Benzamide Derivative AH0109 against HIV-1 Infection","year":2013,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Lamivudine; Virology; Reverse transcriptase; Raltegravir; Zidovudine; Nevirapine; Biology; Human immunodeficiency virus (HIV); Viral replication; Drug; Benzamide; Viral disease; Pharmacology; Virus; Chemistry; Viral load; RNA; Biochemistry; Stereochemistry; Hepatitis B virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005874859,0.0001556635,0.0001085329,0.0001288027,0.00006769074,0.00009454489,0.0001402343,0.0001131914,0.001039687],"category_scores_gemma":[0.00009006448,0.00004169519,0.0001169905,0.00006919444,0.00008051752,0.00008147689,0.00005684565,0.0001709357,0.0001837212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001137411,"about_ca_system_score_gemma":0.0001122916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006720095,"about_ca_topic_score_gemma":0.0005900018,"domain_scores_codex":[0.9999715,0.000005157925,0.000002468649,0.000004658472,0.000008709191,0.000007521861],"domain_scores_gemma":[0.9999681,0.000008014789,0.000006304237,0.000001929949,0.000005764667,0.000009995545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001184475,0.00004671819,0.0002006474,0.00004723775,0.000003825114,0.00004414285,0.000007106998,0.0002408665,0.9962691,0.0000868648,0.00003614543,0.002898907],"study_design_scores_gemma":[0.00003986198,0.001447293,0.004292793,0.00001115845,0.00001453794,0.0002576499,0.00001777696,0.001345113,0.9895905,0.00005351657,0.002921128,0.0000087457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938133,0.002016394,0.00131803,0.00004061565,0.0000155702,0.00003880443,0.0002993121,0.00001720708,0.002440779],"genre_scores_gemma":[0.9948503,0.0009030065,0.00154089,0.00003677791,0.000008273923,0.00001569981,0.0007301696,0.000005365184,0.001909432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001039687,"threshold_uncertainty_score":0.00347811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01110491946146397,"score_gpt":0.2424251208578267,"score_spread":0.2313202013963628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}