{"id":"W2145945926","doi":"10.1095/biolreprod.113.116764","title":"Activation of 5′ Adenosine Monophosphate-Activated Protein Kinase Blocks Cumulus Cell Expansion Through Inhibition of Protein Synthesis During In Vitro Maturation in Swine1","year":2014,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministère de l'Agriculture, des Pêcheries et de l'Alimentation; Université Laval","funders":"National Institutes of Health","keywords":"AMPK; Protein kinase A; Cell biology; Biology; AMP-activated protein kinase; Phosphorylation; Activator (genetics); Cycloheximide; Kinase; Adenosine monophosphate; Protein phosphorylation; Adenosine; Biochemistry; Protein biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008477648,0.0001848446,0.0005733306,0.0002982814,0.00003335332,0.000001300908,0.00005334331,0.0003424082,0.00001588411],"category_scores_gemma":[0.001473919,0.000165022,0.00007026134,0.0005045982,0.0002505583,0.000223771,0.00003392877,0.0002411651,9.906197e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001127029,"about_ca_system_score_gemma":0.00005452629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005553243,"about_ca_topic_score_gemma":0.000004186502,"domain_scores_codex":[0.9977985,0.000357223,0.0008095432,0.000722957,0.0001210999,0.0001906451],"domain_scores_gemma":[0.9984205,0.00004278951,0.000648833,0.000584082,0.0002804121,0.0000234156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02545132,0.0007386983,0.004334415,0.0005232659,0.00001642886,8.848714e-7,0.0003424833,0.00004370505,0.9630854,0.00001670279,0.000001427994,0.005445268],"study_design_scores_gemma":[0.001006993,0.0004011634,0.2091347,0.000321138,0.00001400296,0.000003627096,0.00009134968,0.00004607298,0.7884565,0.0004107555,0.00002033707,0.00009339232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968702,0.0005090508,0.0002963131,0.0005658598,0.00009943842,0.001559811,0.00000530823,0.00002974997,0.00006429003],"genre_scores_gemma":[0.9978117,0.00003820842,0.001756022,0.000003444999,0.0001066136,0.000152529,0.00007421851,0.00001407434,0.00004321345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2048003,"threshold_uncertainty_score":0.6729403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530768220351843,"score_gpt":0.2493419382015281,"score_spread":0.2340342559980097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}