{"id":"W2145980028","doi":"10.1002/stem.1677","title":"Erythropoiesis from Human Embryonic Stem Cells Through Erythropoietin-Independent AKT Signaling","year":2014,"lang":"en","type":"article","venue":"Stem Cells","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stemcell Technologies","funders":"Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Cancer Institute; University of California, Los Angeles; National Institutes of Health; Ariad Pharmaceuticals; California Institute for Regenerative Medicine","keywords":"Erythropoiesis; Biology; Erythropoietin; Cell biology; Embryonic stem cell; Stem cell; Erythropoietin receptor; Progenitor cell; Protein kinase B; Signal transduction; Internal medicine; Endocrinology; Biochemistry; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004267554,0.0005767091,0.001072953,0.0001379013,0.0004359287,0.00007028267,0.0003079516,0.0004753145,0.003251698],"category_scores_gemma":[0.000006270199,0.0005152008,0.0004551366,0.0002879874,0.0002696202,0.0001683217,0.0001762629,0.0006525409,0.003355926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002076188,"about_ca_system_score_gemma":0.000122056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002955092,"about_ca_topic_score_gemma":0.00005116946,"domain_scores_codex":[0.9962369,0.0004050054,0.0008141013,0.001075877,0.0006640185,0.0008041285],"domain_scores_gemma":[0.9975591,0.0003597235,0.0003977483,0.001145095,0.0002035809,0.0003347029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002489783,0.0003458441,0.000736892,0.0002851579,0.0002829544,0.00007789791,0.001290455,0.0001565039,0.9736753,0.0006695616,0.01930947,0.002921005],"study_design_scores_gemma":[0.00401616,0.001448969,0.0004166387,0.0003443403,0.0004170775,0.0000339173,0.002872352,0.000174578,0.8920957,0.0006848348,0.09672217,0.0007731963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745772,0.0007506709,0.003009633,0.0007026091,0.003708992,0.0007796639,0.00006277624,0.0004455093,0.01596294],"genre_scores_gemma":[0.9771904,0.0001409912,0.001026752,0.002066684,0.001571918,0.00003496744,0.00007368344,0.0001348325,0.01775973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08157951,"threshold_uncertainty_score":0.9997299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02538829539739995,"score_gpt":0.2584947221346817,"score_spread":0.2331064267372817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}