{"id":"W2146014904","doi":"10.1002/anie.200704708","title":"Chemodivergence in Enantioselective Desymmetrization of Diazabicycles: Ring‐Opening versus Reductive Arylation","year":2008,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Desymmetrization; Enantioselective synthesis; Ring (chemistry); Chemistry; Stereochemistry; Combinatorial chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379573,0.0001452814,0.0001967846,0.000327085,0.00007421098,0.000012159,0.0002066778,0.0001216376,0.0004457779],"category_scores_gemma":[0.0009965207,0.0001590214,0.0001041653,0.0006399732,0.00008717776,0.0004928726,0.00004983274,0.0001382241,0.00001290836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003449053,"about_ca_system_score_gemma":0.00005442735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002542329,"about_ca_topic_score_gemma":0.00001458797,"domain_scores_codex":[0.9986694,0.00001017105,0.0003748237,0.0003177353,0.0004681973,0.0001596176],"domain_scores_gemma":[0.9989432,0.0002587489,0.0003085489,0.0001426463,0.0003043819,0.00004244179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008189102,0.0005630125,0.05411608,0.00006673125,0.000354897,0.00002200344,0.002110667,0.0005107899,0.921137,0.0006812998,0.001085173,0.01853345],"study_design_scores_gemma":[0.0007529811,0.00001618311,0.01460834,0.00008402268,0.00002641218,0.000007325257,0.0003920707,0.000430152,0.9831722,0.0001834251,0.000169927,0.0001569764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9171827,0.0001538994,0.005773251,0.0001056139,0.0006230907,0.00008415635,0.00008378657,0.00005229724,0.07594121],"genre_scores_gemma":[0.9980901,0.0002955309,0.0003839363,0.000009088527,0.0005044258,0.00003685458,0.0004672801,0.0000153985,0.0001973792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08090741,"threshold_uncertainty_score":0.6484705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02635953687998429,"score_gpt":0.2559733388458993,"score_spread":0.229613801965915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}