{"id":"W2146038209","doi":"10.1093/humrep/del464","title":"Impaired migration of trophoblast cells caused by simvastatin is associated with decreased membrane IGF-I receptor, MMP2 activity and HSP27 expression","year":2006,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; Tel Aviv University","keywords":"Trophoblast; Matrigel; Simvastatin; Biology; Internal medicine; Endocrinology; Receptor; Placenta; Cell biology; Andrology; Cell; Medicine; Biochemistry; Fetus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001049749,0.0003025044,0.0002726691,0.0001706466,0.0001315665,0.0001450729,0.00009375323,0.0001778872,0.001831428],"category_scores_gemma":[0.0001123203,0.0001230162,0.0002680769,0.0001128544,0.0002406413,0.00009178158,0.0001432181,0.0003413816,0.0003768789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000235287,"about_ca_system_score_gemma":0.0001845259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001448921,"about_ca_topic_score_gemma":0.001155452,"domain_scores_codex":[0.9999139,0.00001818382,0.00001027081,0.00001557598,0.00001918679,0.00002280088],"domain_scores_gemma":[0.9999388,0.0000115124,0.00001831257,0.000007788387,0.000006806421,0.00001667741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004895105,0.00001561781,0.0006165545,0.0000347306,0.000007860514,0.0001028168,0.00002352726,0.0000147924,0.9979001,0.00002539264,0.00002073218,0.0007483251],"study_design_scores_gemma":[0.00005699494,0.0009893844,0.03200408,0.000008536364,0.00004848473,0.001141091,0.00009722175,0.0006376086,0.9625125,0.00004894704,0.002450179,0.000004930011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946792,0.00275552,0.001411215,0.00007536654,0.00002052372,0.00001776715,0.0001940577,0.00004555632,0.0008008436],"genre_scores_gemma":[0.995802,0.001599891,0.0009351271,0.00002176524,0.000007854744,0.00002823152,0.0003574956,0.000008422081,0.001239252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001831428,"threshold_uncertainty_score":0.006126761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433162036013796,"score_gpt":0.238280620922461,"score_spread":0.223949000562323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}