{"id":"W2146100735","doi":"10.2337/db05-1378","title":"Analysis of T-Cell Assays to Measure Autoimmune Responses in Subjects With Type 1 Diabetes","year":2006,"lang":"en","type":"article","venue":"Diabetes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Autoantibody; Medicine; Peripheral blood mononuclear cell; Immunology; Immune system; Autoimmune disease; Type 1 diabetes; Diabetes mellitus; Type 2 diabetes; Internal medicine; T cell; Endocrinology; Antibody; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003072752,0.0001767052,0.0003566301,0.0002922449,0.00003307572,0.00002218357,0.0001799029,0.000125659,0.00001860575],"category_scores_gemma":[0.0001321795,0.0001575114,0.0001161829,0.001224653,0.00005104787,0.000004847037,0.00005420222,0.00006555959,0.000005509396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001547511,"about_ca_system_score_gemma":0.00006316579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006986869,"about_ca_topic_score_gemma":0.0002086924,"domain_scores_codex":[0.9987698,0.00009781277,0.00024222,0.000316576,0.0001775752,0.0003959905],"domain_scores_gemma":[0.9993376,0.00005334589,0.0001074145,0.0003131864,0.000140143,0.00004832499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003095585,0.0001161164,0.4842219,0.00001023732,0.0002023656,4.198568e-7,0.00001536722,0.0009576937,0.5139334,0.000005428826,0.0002647391,0.0002413429],"study_design_scores_gemma":[0.0005083389,0.0003826184,0.4431688,0.00002785187,0.0002332874,1.270815e-8,0.00005590147,0.0001658383,0.5542531,0.00001907255,0.000941034,0.0002440735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961981,0.001700881,0.000004876604,0.00006401894,0.00003567115,0.0001390334,0.0000458152,0.00001426034,0.001797368],"genre_scores_gemma":[0.998937,0.00001733548,0.0001722447,0.0001531713,0.00002049392,0.00002101231,0.0002104762,0.00002408218,0.0004442292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04105305,"threshold_uncertainty_score":0.6423128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005033736126241272,"score_gpt":0.2041203855201997,"score_spread":0.1990866493939585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}