{"id":"W2146189359","doi":"10.1006/jmcc.2001.1376","title":"The Molecular Physiology of the Cardiac Transient Outward Potassium Current (Ito) in Normal and Diseased Myocardium","year":2001,"lang":"en","type":"review","venue":"Journal of Molecular and Cellular Cardiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; Toronto General Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Cardiac transient outward potassium current; Cardiac electrophysiology; Repolarization; Cardiac action potential; Electrophysiology; Potassium channel; Myocyte; Cardiac cell; Ion channel; Chemistry; Internal medicine; Cardiac muscle; Biology; Patch clamp; Biophysics; Neuroscience; Cell biology; Endocrinology; Biochemistry; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008137384,0.0005111712,0.003567616,0.000212498,0.0001164204,0.00001275122,0.000272579,0.0004900993,0.000002154913],"category_scores_gemma":[0.0001289261,0.0002801472,0.00288264,0.0003283255,0.0007021744,0.00002840078,0.0001691464,0.001551334,0.000001100019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007957085,"about_ca_system_score_gemma":0.0005228849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005092531,"about_ca_topic_score_gemma":4.40768e-7,"domain_scores_codex":[0.995683,0.001870643,0.001144618,0.0004181668,0.0003453004,0.0005382784],"domain_scores_gemma":[0.9980479,0.0002361256,0.0007211705,0.0006091515,0.00017767,0.0002079543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001654879,0.0002638382,0.0007553844,0.01124931,0.01033371,0.008828561,0.0002916407,0.0003999571,0.07506294,0.0007043695,0.0007277526,0.8897277],"study_design_scores_gemma":[0.002438159,0.001006835,0.004669033,0.003529874,0.01119437,0.006942406,0.00007645354,0.000009060414,0.0009688083,0.000274315,0.9682573,0.0006333539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05400063,0.9435383,0.0002091177,0.000214623,0.001229243,0.0006648703,0.00002804381,0.000004540483,0.0001106463],"genre_scores_gemma":[0.1152534,0.8840989,0.00001211737,0.00006826352,0.0004568558,0.00002527011,0.00002880755,0.00004325873,0.0000131276],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9675296,"threshold_uncertainty_score":0.9999651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009711881118575705,"score_gpt":0.257817946146306,"score_spread":0.2481060650277303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}