{"id":"W2146367607","doi":"10.1136/gut.2008.150888","title":"Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse","year":2008,"lang":"en","type":"article","venue":"Gut","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":319,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vernon Jubilee Hospital; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Spermine; Ethylmorphine; Spermidine; Putrescine; Chemistry; Biochemistry; Hydroxylation; Microsome; Demethylation; Acetanilide; Pharmacology; Biology; Enzyme; Organic chemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003234936,0.001013816,0.0007187887,0.0008677478,0.0002361592,0.0004418296,0.0005293165,0.0008552689,0.002539179],"category_scores_gemma":[0.0002388986,0.0003475081,0.000418635,0.00031035,0.0005629307,0.0004753937,0.0002956275,0.001751278,0.001218657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004262253,"about_ca_system_score_gemma":0.0003554369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004030197,"about_ca_topic_score_gemma":0.0007741067,"domain_scores_codex":[0.999694,0.00004842578,0.00003165692,0.00006123945,0.00008097117,0.00008373715],"domain_scores_gemma":[0.9993687,0.00006597459,0.0002229018,0.00005099468,0.00004601496,0.0002454322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005067295,0.0002785758,0.0001988706,0.00006335352,0.000007121122,0.00005958951,0.00001742956,0.00004451605,0.9974668,0.00004816345,0.00006739741,0.001241413],"study_design_scores_gemma":[0.0004020501,0.006632318,0.008447464,0.00008313682,0.00007849991,0.0009219989,0.00007661421,0.001071643,0.978053,0.0001339239,0.004081821,0.00001761466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926633,0.002174169,0.002238767,0.0003758169,0.00007667267,0.0000838597,0.0007102005,0.0002721559,0.001405067],"genre_scores_gemma":[0.9742332,0.003888397,0.01057158,0.0003875828,0.00008504497,0.0003142803,0.001678152,0.000179766,0.008662018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002539179,"threshold_uncertainty_score":0.008494437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07093346993829336,"score_gpt":0.2586804721698651,"score_spread":0.1877470022315718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}