{"id":"W2146377217","doi":"10.1139/y09-076","title":"c-Ski, Smurf2, and Arkadia as regulators of TGF-β signaling: new targets for managing myofibroblast function and cardiac fibrosisThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"SMAD; Mediator; Cardiac fibrosis; Transforming growth factor; Extracellular matrix; Cell biology; Myofibroblast; Transforming growth factor beta; Receptor; Signal transduction; Fibrosis; R-SMAD; Biology; Cancer research; Chemistry; Medicine; Internal medicine; Endoglin; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002707795,0.0004773151,0.000415258,0.0004093089,0.0003340536,0.0008330624,0.000293567,0.0004270676,0.00266337],"category_scores_gemma":[0.00009532834,0.0001585344,0.0003090456,0.0003168454,0.0004637911,0.0005507778,0.0003219816,0.001180217,0.0007833749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000712967,"about_ca_system_score_gemma":0.0006345015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001123561,"about_ca_topic_score_gemma":0.004722108,"domain_scores_codex":[0.9999374,0.000008149937,0.00000459342,0.000008880738,0.00002487664,0.00001598765],"domain_scores_gemma":[0.9999456,0.000006935459,0.00001303316,0.000002246775,0.00001102329,0.00002117441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001492518,0.0002679383,0.001645744,0.001852321,0.00009625961,0.001464425,0.0002303917,0.00107585,0.6876001,0.009676529,0.005104335,0.2894937],"study_design_scores_gemma":[0.0004824043,0.001887307,0.01279908,0.0002494022,0.0003260287,0.005895184,0.0004158716,0.002036975,0.493992,0.003971021,0.4778289,0.0001159155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1717116,0.7909068,0.008210743,0.004726928,0.000941163,0.0001162657,0.0002838801,0.000242162,0.02286044],"genre_scores_gemma":[0.4044663,0.553766,0.01094159,0.00123215,0.000613189,0.0001073471,0.0006865458,0.00005240395,0.02813452],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00266337,"threshold_uncertainty_score":0.008909881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082358938019723,"score_gpt":0.2300440229850994,"score_spread":0.2192204336049022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}