{"id":"W2146387333","doi":"10.1002/jcb.10500","title":"Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Organoselenium and organotellurium chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Laurentian University","funders":"","keywords":"Ebselen; Cycloheximide; Apoptosis; Programmed cell death; Pharmacology; Antioxidant; Chemistry; Necrosis; Neuroprotection; Glutathione; Glutathione peroxidase; Biochemistry; Biology; Medicine; Enzyme; Superoxide dismutase; Protein biosynthesis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001561897,0.0003257851,0.0002431927,0.0002199295,0.0001077509,0.0002374052,0.0001422483,0.0002775661,0.00109732],"category_scores_gemma":[0.0001471506,0.0001104653,0.0002278449,0.000146779,0.000250578,0.0002319065,0.0002395838,0.0003263913,0.0002778293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002011856,"about_ca_system_score_gemma":0.0001257372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000136347,"about_ca_topic_score_gemma":0.0001792803,"domain_scores_codex":[0.9998698,0.0000382517,0.00001623155,0.00001931009,0.00002627605,0.00003018379],"domain_scores_gemma":[0.9999188,0.00002036344,0.00002171726,0.0000146737,0.00001085256,0.00001355648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001183244,0.00001807692,0.00007576001,0.00002443469,0.000005483685,0.0000550663,0.00001272269,0.00002948482,0.9989592,0.0000697272,0.00001149586,0.0006201912],"study_design_scores_gemma":[0.00001064299,0.0003016159,0.0005317016,0.000002203189,0.000006400127,0.0001137771,0.00001042207,0.0001110964,0.9984769,0.00003819281,0.0003959938,9.954266e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950579,0.0013237,0.002272492,0.000066646,0.00001754319,0.00001763264,0.00007248145,0.00005924486,0.00111225],"genre_scores_gemma":[0.9957649,0.001063927,0.001456382,0.00003796294,0.000006861693,0.00002157046,0.0001738956,0.000008095442,0.001466384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109732,"threshold_uncertainty_score":0.003670931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03073638370343742,"score_gpt":0.321302312067107,"score_spread":0.2905659283636696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}