{"id":"W2146403889","doi":"10.1534/genetics.114.168609","title":"The Switch from Fermentation to Respiration in <i>Saccharomyces cerevisiae</i> Is Regulated by the Ert1 Transcriptional Activator/Repressor","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Repressor; Saccharomyces cerevisiae; Glyoxylate cycle; Promoter; Gene; Biochemistry; Gene expression; Pyruvate decarboxylase; Gluconeogenesis; Activator (genetics); Ethanol fermentation; Catabolite repression; Regulation of gene expression; Gene cluster; Fermentation; Alcohol dehydrogenase; Mutant; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003151733,0.00013798,0.0000911853,0.00002297978,0.0001995674,0.0001015751,0.0003691289,0.0001152403,0.00003386375],"category_scores_gemma":[0.00005638784,0.00009283564,0.00005172068,0.0001479431,0.00006236041,0.000003703651,0.00008432664,0.0001156196,0.00002655473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001944426,"about_ca_system_score_gemma":0.00004748797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006619999,"about_ca_topic_score_gemma":0.0001558476,"domain_scores_codex":[0.9986309,0.000178524,0.0002411828,0.0003513582,0.0003126225,0.0002854353],"domain_scores_gemma":[0.9992892,0.00003841924,0.00005273666,0.0004471933,0.0000895391,0.00008291229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001200475,0.00002597981,0.001689846,0.000003419915,0.00002167539,1.107707e-7,0.0001742093,0.0003273335,0.9731122,0.00002710442,0.0121915,0.01230663],"study_design_scores_gemma":[0.0004086866,0.0001638773,0.01931468,0.000009187178,0.000008366504,0.000001054718,0.00006918576,0.0007341121,0.8038489,0.000399531,0.1749116,0.0001307806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921331,0.001287059,0.001114074,0.004680619,0.000120461,0.0003418843,0.00006514721,0.000006039674,0.000251588],"genre_scores_gemma":[0.9967472,0.0003816999,0.0002717264,0.001190033,0.0002632374,0.00006680873,0.0001595951,0.00002082917,0.0008988896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1692633,"threshold_uncertainty_score":0.3785727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01302280114100733,"score_gpt":0.2690359943636727,"score_spread":0.2560131932226654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}