{"id":"W2146484777","doi":"10.1152/ajplung.00030.2009","title":"Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Efferocytosis; Proinflammatory cytokine; Cell biology; Cystic fibrosis transmembrane conductance regulator; Inflammation; RHOA; Phagocytosis; Apoptosis; Biology; Immunology; Cystic fibrosis; Cancer research; Signal transduction; Macrophage; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002620996,0.0003590391,0.0006459207,0.0002780933,0.0001937894,0.0003836252,0.0002998584,0.0004524181,0.001100801],"category_scores_gemma":[0.0002718569,0.0001403144,0.0003403885,0.0001508683,0.0003132125,0.0002358386,0.0001841363,0.0007988749,0.0004606709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002203432,"about_ca_system_score_gemma":0.0003764767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003887346,"about_ca_topic_score_gemma":0.0006443279,"domain_scores_codex":[0.9996917,0.0000750264,0.00003847037,0.00004337427,0.0000622824,0.00008903633],"domain_scores_gemma":[0.9997701,0.00004677112,0.00004644248,0.0000334904,0.00002769343,0.00007554882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003327858,0.0002095795,0.0001168647,0.00004390454,0.000008238734,0.0000369962,0.00001376603,0.00005131116,0.9972813,0.00009316662,0.00008560595,0.001726525],"study_design_scores_gemma":[0.0001368912,0.002532431,0.004335331,0.00001548977,0.00003281807,0.0004992051,0.00003671361,0.001680085,0.9875736,0.00006313415,0.003085918,0.000008333568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942773,0.002004002,0.001702738,0.0002009551,0.00007336277,0.00004655774,0.0001387992,0.0001358872,0.001420478],"genre_scores_gemma":[0.9956194,0.0009134987,0.001538025,0.00008409001,0.00002294114,0.00005167111,0.0003284877,0.00002134216,0.001420725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001100801,"threshold_uncertainty_score":0.003682554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003919865172000544,"score_gpt":0.1990581649510074,"score_spread":0.1951382997790068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}