{"id":"W2146625037","doi":"10.1038/embor.2013.36","title":"Plasma membrane—endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis","year":2013,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Endoplasmic reticulum; Phosphatidylethanolamine; Membrane contact site; Organelle; Phosphatidylcholine; Cell biology; Enzyme; Membrane; Chemistry; Biochemistry; Biology; Phospholipid; Membrane protein; Integral membrane protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002134181,0.000242097,0.000258865,0.00004715956,0.00009707185,0.00005158428,0.0001077047,0.0002195782,0.001149886],"category_scores_gemma":[0.0001148524,0.0002241072,0.000183926,0.00008404595,0.00005771461,0.00001630017,0.00003722223,0.000103545,0.00007800015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001228784,"about_ca_system_score_gemma":0.0000509472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001385687,"about_ca_topic_score_gemma":0.0000696334,"domain_scores_codex":[0.998394,0.00003837447,0.0004865399,0.0005314248,0.0002171905,0.000332484],"domain_scores_gemma":[0.9988643,0.0000180379,0.0002191373,0.0006253048,0.0001208959,0.000152313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003434339,0.00005281834,0.01041116,0.00002977696,0.00007029327,0.0001444822,0.00003246475,0.00003719309,0.9873947,0.00002938903,0.001195544,0.0005678662],"study_design_scores_gemma":[0.0002424885,0.00007483573,0.0115313,0.00002967441,0.00005491439,0.0003814424,0.00002905275,0.0002311957,0.9385782,0.00009342562,0.04844402,0.0003094423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934752,0.000466236,0.000412621,0.0002325726,0.000298807,0.0003602342,0.000007149429,0.00004920094,0.004697988],"genre_scores_gemma":[0.9946064,0.0002150763,0.0003829284,0.0001546307,0.0002075671,0.00007679593,0.001524084,0.00004327142,0.002789198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04881646,"threshold_uncertainty_score":0.9997632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006345985239220282,"score_gpt":0.1991741038213984,"score_spread":0.1928281185821781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}