{"id":"W2146652817","doi":"10.1002/pbc.20305","title":"Lack of response of a metastatic renal perivascular epithelial cell tumor (PEComa) to successive courses of DTIC based-therapy and imatinib mesylate","year":2005,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Medicine; Perivascular Epithelioid Cell; Dacarbazine; Imatinib mesylate; Imatinib; Tyrosine-kinase inhibitor; Discontinuation; Regimen; Clear-cell sarcoma; PDGFRA; Pathology; Oncology; Chemotherapy; Internal medicine; Epithelioid cell; Sarcoma; Cancer; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000833466,0.0002245756,0.0008527767,0.0004455268,0.00004111556,0.000009714279,0.0002158662,0.00004513079,0.0006126756],"category_scores_gemma":[0.0003628979,0.0001900583,0.0001851822,0.0006530978,0.0001840377,0.00007046367,0.00007539584,0.0001528014,0.000006194134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004343524,"about_ca_system_score_gemma":0.0007873093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004627803,"about_ca_topic_score_gemma":0.00005460032,"domain_scores_codex":[0.9974694,0.0002952914,0.000702048,0.0003521284,0.0008019813,0.0003791342],"domain_scores_gemma":[0.9977521,0.0006617765,0.0004044554,0.0004660572,0.0004744913,0.0002411497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01466029,0.00298154,0.1444313,0.003319462,0.0007333983,0.00007536249,0.002836524,0.001562394,0.8236948,0.00003607624,0.0008354092,0.004833371],"study_design_scores_gemma":[0.01834641,0.004057942,0.2865008,0.0003771883,0.002155167,0.00003158017,0.0002481763,0.001950901,0.6853141,0.0000228868,0.0005520409,0.0004427808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988992,0.008875568,0.00007032108,0.0009650053,0.00003682503,0.0007724832,0.0002268283,0.00001725912,0.00004367629],"genre_scores_gemma":[0.9911166,0.0009730939,0.007226773,0.000219024,0.0002204079,0.0000947602,0.000004379445,0.00004413435,0.0001007782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1420695,"threshold_uncertainty_score":0.7750354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0625558278530805,"score_gpt":0.3515827918465055,"score_spread":0.289026963993425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}