{"id":"W2146654412","doi":"10.1093/molbev/msq087","title":"Constrained Intron Structures in a Microsporidian","year":2010,"lang":"en","type":"letter","venue":"Molecular Biology and Evolution","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Intron; Biology; Genetics; RNA splicing; Genome; Gene; Group I catalytic intron; Computational biology; splice; Splice site mutation; Evolutionary biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000742585,0.0001062122,0.00009896191,0.0001530969,0.0002085295,0.0002660912,0.000156095,0.000404952,0.0004044975],"category_scores_gemma":[0.0004373697,0.00008351093,0.00006443029,0.0001197166,0.0001894728,0.0001186185,0.0001846151,0.0003448964,0.0003146857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002691977,"about_ca_system_score_gemma":0.0001009669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004128294,"about_ca_topic_score_gemma":0.000714933,"domain_scores_codex":[0.9999279,0.000009371364,0.000005301348,0.00001860334,0.00003009408,0.000008873787],"domain_scores_gemma":[0.9998276,0.00005624228,0.00005001614,0.00002704315,0.00002000643,0.00001901316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001997552,0.00001445537,0.007770318,0.00005137787,0.00000639804,0.001254226,0.00008425033,0.0007386756,0.9793084,0.0005792423,0.0002937413,0.00969917],"study_design_scores_gemma":[0.00009159799,0.0007725657,0.1990135,0.00005617566,0.00007758801,0.0206918,0.0002787345,0.0196363,0.7195249,0.004325892,0.03546384,0.00006700296],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974576,0.000363219,0.001408196,0.0001490744,0.000008065213,0.000002684104,0.00008162887,0.00003055261,0.0004989915],"genre_scores_gemma":[0.9971584,0.0001239909,0.001834977,0.000159841,0.00001259252,0.000006920362,0.0003136251,0.00001016322,0.0003795769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004128294,"threshold_uncertainty_score":0.001953244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003411675725545832,"score_gpt":0.2400027451769462,"score_spread":0.2365910694514004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}