{"id":"W2146666488","doi":"10.1093/cid/cis383","title":"Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study","year":2012,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":240,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut de Readaptation Gingras Lindsay de Montreal; McGill University Health Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Institutes of Health","keywords":"Medicine; Immunology; Viremia; T cell; Aldesleukin; Immune system; Placebo; T-cell receptor; Multicenter trial; Interleukin 2; Internal medicine; Randomized controlled trial; Human immunodeficiency virus (HIV); Multicenter study; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004129948,0.001385102,0.002658795,0.0004012899,0.0004086578,0.001120322,0.0008207576,0.001733882,0.002151314],"category_scores_gemma":[0.002430176,0.0006684784,0.001940731,0.0004497913,0.001199439,0.0008155614,0.000275392,0.002221602,0.0003692889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005134296,"about_ca_system_score_gemma":0.0009589184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003605321,"about_ca_topic_score_gemma":0.0004744812,"domain_scores_codex":[0.9979903,0.001434005,0.0001275332,0.0001564391,0.0001129807,0.0001787707],"domain_scores_gemma":[0.9978133,0.0008051526,0.0005048511,0.0002154411,0.0001246244,0.0005365129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9604734,0.01165716,0.001743708,0.0003319248,0.0008187202,0.0000409499,0.00004712492,0.0002582128,0.006440599,0.00003174041,0.0002237893,0.01793275],"study_design_scores_gemma":[0.6704367,0.3239005,0.003554485,0.0000250087,0.000531437,0.00003629342,0.00001508756,0.0002135254,0.0009843771,0.00003618159,0.0002545263,0.00001172948],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935598,0.003581764,0.000393746,0.0002045706,0.0001279848,0.001325977,0.0002553368,0.0000552743,0.0004954121],"genre_scores_gemma":[0.9942937,0.001771705,0.001041811,0.000422384,0.0003083188,0.001252427,0.0004011823,0.00001607173,0.0004923568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004129948,"threshold_uncertainty_score":0.02184153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01700571334649666,"score_gpt":0.3261453326657808,"score_spread":0.3091396193192842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}