{"id":"W2146666488","doi":"10.1093/cid/cis383","title":"Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study","year":2012,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":240,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut de Readaptation Gingras Lindsay de Montreal; McGill University Health Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Institutes of Health","keywords":"Medicine; Immunology; Viremia; T cell; Aldesleukin; Immune system; Placebo; T-cell receptor; Multicenter trial; Interleukin 2; Internal medicine; Randomized controlled trial; Human immunodeficiency virus (HIV); Multicenter study; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00131783,0.0003066943,0.001553849,0.0003080075,0.00009885403,0.0000148494,0.000131583,0.0001882188,0.00002986451],"category_scores_gemma":[0.003814158,0.0002139276,0.0004358779,0.0001165665,0.0004017298,0.0001328863,0.000111308,0.0003721259,0.00006791944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006693444,"about_ca_system_score_gemma":0.00004847466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002210396,"about_ca_topic_score_gemma":0.00004861942,"domain_scores_codex":[0.9940507,0.003611066,0.00135372,0.0004220537,0.00009064885,0.0004717698],"domain_scores_gemma":[0.9921852,0.006683104,0.0005927705,0.0003189148,0.0001054409,0.0001145609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2614753,0.05350408,0.6721394,0.00006900164,0.0008199056,0.000008590542,0.0004553512,9.65333e-7,0.0007138366,0.000002806371,0.0003329223,0.01047784],"study_design_scores_gemma":[0.6123493,0.01148919,0.3744042,0.0001701123,0.0002379979,3.287071e-7,0.00004314548,0.000003867721,0.001110572,0.00001475516,0.00003484915,0.0001416473],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935734,0.001308669,0.000004322671,0.00001056284,0.0008186984,0.003891813,0.0001005123,0.00004081868,0.000251264],"genre_scores_gemma":[0.9985836,0.0006142309,0.000001744156,0.0000344261,0.00003012854,0.0002607077,0.0001647052,0.00002424652,0.0002861666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.350874,"threshold_uncertainty_score":0.8723714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01700571334649666,"score_gpt":0.3261453326657808,"score_spread":0.3091396193192842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}