{"id":"W2146671198","doi":"10.1002/1097-0215(200002)9999:9999<::aid-ijc1131>3.0.co;2-y","title":"Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model","year":2001,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver General Hospital","funders":"National Cancer Institute; Medizinische Abteilung der Margarete und Walter Lichtenstein-Stiftung; Freiwillige Akademische Gesellschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"LNCaP; Paclitaxel; Prostate cancer; Cancer research; Androgen; In vivo; Medicine; Biology; Internal medicine; Chemotherapy; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001396869,0.0004094256,0.000286407,0.0002993114,0.0001093737,0.0002240277,0.0001833758,0.0001564825,0.0006331101],"category_scores_gemma":[0.00006879081,0.0001689054,0.0002258623,0.000145609,0.000178042,0.0001442823,0.0001611862,0.0005200518,0.0001274529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002535926,"about_ca_system_score_gemma":0.0003614014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007964419,"about_ca_topic_score_gemma":0.002534489,"domain_scores_codex":[0.9998716,0.00001769258,0.000008164647,0.00002247887,0.00004234917,0.00003776303],"domain_scores_gemma":[0.9999309,0.0000108001,0.00001744122,0.000008238068,0.000007475473,0.0000251681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001668282,0.0001335191,0.0001087551,0.00002184053,0.000005666133,0.00002077672,0.000009078009,0.0001601418,0.9977534,0.00006245078,0.00002561626,0.001531801],"study_design_scores_gemma":[0.00004021061,0.002626011,0.00157433,0.000003558199,0.00002142679,0.0001085038,0.00001027727,0.00115246,0.9930615,0.00003086051,0.00136606,0.000004755678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950125,0.0009031796,0.002250553,0.00004790686,0.00004051975,0.00007377504,0.00009713605,0.00008279308,0.001491637],"genre_scores_gemma":[0.9938779,0.0007384563,0.002380501,0.00003768929,0.00001653716,0.00007214724,0.0001487271,0.00001307045,0.002714935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007964419,"threshold_uncertainty_score":0.002117991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006005200248916434,"score_gpt":0.2832176636854044,"score_spread":0.277212463436488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}