{"id":"W2146671198","doi":"10.1002/1097-0215(200002)9999:9999<::aid-ijc1131>3.0.co;2-y","title":"Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model","year":2001,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver General Hospital","funders":"National Cancer Institute; Medizinische Abteilung der Margarete und Walter Lichtenstein-Stiftung; Freiwillige Akademische Gesellschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"LNCaP; Paclitaxel; Prostate cancer; Cancer research; Androgen; In vivo; Medicine; Biology; Internal medicine; Chemotherapy; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002074499,0.00006229938,0.00007926945,0.00005652354,0.00001899528,0.00002185264,0.00005438813,0.00003860739,0.000002260392],"category_scores_gemma":[0.00003337861,0.0000448595,0.00002014479,0.00004582539,0.00003090752,0.00001466454,0.00003041793,0.00004597358,6.961432e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001576253,"about_ca_system_score_gemma":0.00003713438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002033479,"about_ca_topic_score_gemma":0.00004152015,"domain_scores_codex":[0.9993555,0.00002579355,0.0002175377,0.00009832688,0.0002386556,0.00006418262],"domain_scores_gemma":[0.9995049,0.000007502253,0.0001785725,0.00004554945,0.0002313763,0.00003212301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000252607,0.00003719675,0.002507494,0.000009287814,0.00002109299,0.00002242971,0.0001878909,0.002270021,0.98262,0.00009040095,0.0001803734,0.0118012],"study_design_scores_gemma":[0.002387638,0.0004578232,0.0178076,0.0005506384,0.00005357758,0.0004889159,0.0002873923,0.01838389,0.9555381,0.002090884,0.001712689,0.0002408724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932353,0.001176126,0.004783072,0.0005864909,0.00006477161,0.0001098685,0.00001682189,8.887845e-7,0.00002660548],"genre_scores_gemma":[0.9973944,0.001880669,0.0003877715,0.0002099354,0.00007386805,0.000004064825,0.00001273857,0.000006064312,0.00003045469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02708193,"threshold_uncertainty_score":0.1829317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006005200248916434,"score_gpt":0.2832176636854044,"score_spread":0.277212463436488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}