{"id":"W2146790106","doi":"10.1021/ol051428b","title":"Boc-Protected Amines via a Mild and Efficient One-Pot Curtius Rearrangement","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Curtius rearrangement; Chemistry; Carbamate; Sodium azide; Isocyanate; Malonate; Medicinal chemistry; Azide; Organic chemistry; Decarboxylation; Trifluoromethanesulfonate; Derivative (finance); Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004705314,0.001356923,0.0007499708,0.0004689182,0.000462356,0.0002599791,0.001067433,0.000587307,0.003855272],"category_scores_gemma":[0.0004260878,0.0003701778,0.0004272151,0.0003632497,0.0004570089,0.0005622843,0.000918867,0.001177728,0.002466568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004754993,"about_ca_system_score_gemma":0.0007599443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009093445,"about_ca_topic_score_gemma":0.002064712,"domain_scores_codex":[0.9995551,0.0000529295,0.00003543674,0.00009556329,0.0001152728,0.0001458156],"domain_scores_gemma":[0.9998312,0.00003062327,0.00003742272,0.00003352689,0.00002953793,0.00003760632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073582,0.00009738005,0.00006220589,0.000324062,0.00004019311,0.0005675799,0.0001036489,0.0003825027,0.9852138,0.001680097,0.00145202,0.00996916],"study_design_scores_gemma":[0.00007052792,0.0003785089,0.000560981,0.0000166549,0.00002715232,0.0007420984,0.00002077527,0.0008137743,0.9776382,0.00031061,0.01938381,0.00003688977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6993039,0.008868282,0.2115211,0.001774875,0.001342339,0.0028564,0.002308011,0.007560375,0.06446474],"genre_scores_gemma":[0.9217455,0.006699816,0.04736785,0.0005640535,0.0002007684,0.0008278701,0.001492621,0.0004769913,0.02062451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003855272,"threshold_uncertainty_score":0.01289713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006131466836369776,"score_gpt":0.1975657822224717,"score_spread":0.1914343153861019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}