{"id":"W2146790106","doi":"10.1021/ol051428b","title":"Boc-Protected Amines via a Mild and Efficient One-Pot Curtius Rearrangement","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Curtius rearrangement; Chemistry; Carbamate; Sodium azide; Isocyanate; Malonate; Medicinal chemistry; Azide; Organic chemistry; Decarboxylation; Trifluoromethanesulfonate; Derivative (finance); Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006394159,0.0001230016,0.0001264283,0.00002495061,0.00005873203,0.00002223705,0.0001002632,0.00006550091,0.0001381959],"category_scores_gemma":[0.00003341198,0.0001098506,0.00006433498,0.00008786198,0.00004979061,0.000001560241,0.00007758883,0.00005611005,0.00002424835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002267201,"about_ca_system_score_gemma":0.000005470733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002279039,"about_ca_topic_score_gemma":0.00002631524,"domain_scores_codex":[0.9992206,0.00002219918,0.0001450047,0.0003007274,0.0001136376,0.0001978347],"domain_scores_gemma":[0.999631,0.00000643045,0.00004605907,0.0002259129,0.00001982115,0.00007078653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001459328,0.00005475089,0.000177634,0.00000807166,0.0000661857,9.453333e-7,0.00002587243,0.00001067513,0.9943914,0.000001083621,0.001516432,0.003732383],"study_design_scores_gemma":[0.0003090865,0.00002553451,0.0009986153,0.000009832467,0.00004983244,0.000004023047,0.000009903126,0.0001672882,0.9879074,0.00000156507,0.01035516,0.0001618178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911641,0.0003513778,0.001536057,0.006758328,0.00001969805,0.00009210296,0.000003360092,0.00001487063,0.00006006016],"genre_scores_gemma":[0.9967844,0.00005817954,0.0007483721,0.001992359,0.0002853968,0.00001016472,0.00002214985,0.00001801271,0.00008092083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008838723,"threshold_uncertainty_score":0.4479579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006131466836369776,"score_gpt":0.1975657822224717,"score_spread":0.1914343153861019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}