{"id":"W2146839729","doi":"10.1073/pnas.1017496108","title":"An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ <i>wingless</i> signaling pathway","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":333,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health; York University; U.S. Department of Defense","keywords":"Wnt signaling pathway; Biology; RNA interference; Adherens junction; Catenin; Phenotypic screening; Cell biology; Signal transduction; Cancer research; Transcription factor; Phenotype; Computational biology; Gene; Cell; Genetics; Cadherin; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0393778329907007,"score_gpt":0.255894152420257,"score_spread":0.2165163194295563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}