{"id":"W2146865613","doi":"10.1261/rna.5241404","title":"Premature termination codons do not affect the rate of splicing of neighboring introns","year":2004,"lang":"en","type":"article","venue":"RNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Council for Research in the Social Sciences, Columbia University; Brandeis University; National Institutes of Health; Connaught Fund; Howard Hughes Medical Institute","keywords":"Biology; Intron; Exon; Nonsense-mediated decay; RNA splicing; Polyadenylation; Precursor mRNA; Molecular biology; Messenger RNA; Gene; Genetics; Mature messenger RNA; RNA; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003747985,0.0002990593,0.000255952,0.0001508971,0.0001092425,0.0004522119,0.0002435132,0.0003250455,0.000978556],"category_scores_gemma":[0.001030417,0.0001893395,0.000218293,0.0001003279,0.0003984631,0.0002297791,0.0001697283,0.0004426641,0.0004735118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002023167,"about_ca_system_score_gemma":0.0001683446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002751744,"about_ca_topic_score_gemma":0.0003565244,"domain_scores_codex":[0.9994777,0.0001269281,0.00006512258,0.0001203934,0.0001557176,0.00005411837],"domain_scores_gemma":[0.9987135,0.0005723438,0.0003591244,0.0001517318,0.0001041336,0.00009917864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005894504,0.00001047995,0.0005074603,0.00001394543,0.000003778003,0.00006060974,0.00001074249,0.00003350921,0.9983457,0.0000631378,0.000008002419,0.0008837272],"study_design_scores_gemma":[0.000005968387,0.0002078783,0.004331157,0.00000247715,0.00001467489,0.0005060245,0.00001486825,0.0007321804,0.9933843,0.00005771867,0.0007387289,0.000004060952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949527,0.0005228157,0.003515104,0.00003743871,0.00002184441,0.00001081399,0.00007129556,0.00007669005,0.0007913246],"genre_scores_gemma":[0.9970065,0.0001967885,0.001986511,0.00002177725,0.000008100746,0.000008615128,0.000187426,0.00003946755,0.0005448045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000978556,"threshold_uncertainty_score":0.003273606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009375956725330056,"score_gpt":0.2763187049925417,"score_spread":0.2669427482672117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}