{"id":"W2146891480","doi":"10.1002/jps.22782","title":"Osmotic Release of Bioactive VEGF from Biodegradable Elastomer Monoliths is the Same In Vivo As In Vitro","year":2011,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Trehalose; In vivo; In vitro; Osmotic pressure; Chemistry; Biophysics; Elastomer; Albumin; Biomedical engineering; Biochemistry; Biology; Organic chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002452139,0.0003988782,0.0002709399,0.0001411803,0.0001414057,0.0003406048,0.0001196125,0.0002814724,0.0006978562],"category_scores_gemma":[0.0002437278,0.0002120062,0.0003080904,0.0000913053,0.0002554086,0.0004673026,0.0001211271,0.0005544503,0.0001701008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002116709,"about_ca_system_score_gemma":0.0002183445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000408953,"about_ca_topic_score_gemma":0.0005880292,"domain_scores_codex":[0.9998804,0.00001743667,0.000009914818,0.00002424103,0.00003458269,0.00003342969],"domain_scores_gemma":[0.9997479,0.00006305679,0.00008425683,0.00002874812,0.00002008832,0.00005591041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001793683,0.00002318325,0.00008223733,0.000009756741,0.00000413271,0.00001811069,0.000006750342,0.00002412591,0.9990104,0.00002408921,0.00001408142,0.000603748],"study_design_scores_gemma":[0.00001552444,0.0002793841,0.001235502,0.00000183483,0.00001281505,0.00008546811,0.000007803068,0.0002483808,0.99768,0.000013037,0.0004169602,0.000003139544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951065,0.001282648,0.002265086,0.0000658845,0.00006194035,0.00001428666,0.000193377,0.00005232491,0.0009581094],"genre_scores_gemma":[0.9959643,0.0004518057,0.0013993,0.00003986575,0.00002187559,0.0000138769,0.0002507505,0.0000354152,0.001822836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006978562,"threshold_uncertainty_score":0.002334535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04510003460901592,"score_gpt":0.3318206993629267,"score_spread":0.2867206647539108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}