{"id":"W2146915953","doi":"10.1158/1078-0432.ccr-11-3085","title":"Reovirus as a Viable Therapeutic Option for the Treatment of Multiple Myeloma","year":2012,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary; University of Alberta; Alberta Health Services","funders":"","keywords":"Multiple myeloma; Oncolytic virus; Bone marrow; Population; Ex vivo; Cancer research; Haematopoiesis; In vivo; Medicine; Stem cell; Immunology; Biology; Immune system; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002759401,0.0001223549,0.0002034799,0.00005042104,0.0002153,0.00001885024,0.0003643641,0.0001800712,0.0001413111],"category_scores_gemma":[0.0003720272,0.00007917084,0.0002328251,0.0001884873,0.0004409793,0.000005467136,0.00007320981,0.0001754467,0.00004454724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007859824,"about_ca_system_score_gemma":0.0003599987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000249904,"about_ca_topic_score_gemma":0.0003476336,"domain_scores_codex":[0.9978104,0.0004920583,0.0003363569,0.0003223336,0.0003959609,0.0006428913],"domain_scores_gemma":[0.997803,0.0009248353,0.00006561867,0.000674711,0.0003565953,0.0001751983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02326498,0.001604895,0.03068899,0.00004402609,0.0005566532,7.308146e-7,0.0002130884,0.00008261205,0.4673484,0.00016852,0.001647584,0.4743795],"study_design_scores_gemma":[0.002638425,0.01573076,0.004858465,0.00001170863,0.00003057439,0.000001328402,0.0001517057,0.0003108841,0.5962865,0.0002202852,0.3796226,0.0001367663],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744529,0.02276055,0.0002289476,0.0007718421,0.0002436731,0.001244847,0.0000426663,0.000007086486,0.0002474906],"genre_scores_gemma":[0.980544,0.01473071,0.00008220215,0.0001666447,0.001256397,0.001021413,0.00002465772,0.00003537002,0.002138547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4742427,"threshold_uncertainty_score":0.3228493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2658909137045665,"score_gpt":0.5385767344523856,"score_spread":0.2726858207478192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}